Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.58 |
| ▸ | BAX | Q07812 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5946346 | 0.93 | MMP2 (0.49) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| SCHEMBL12994049 | 0.92 | ESR1 (0.70) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| Bisphenol A SCHEMBL2463040 | 0.90 | ESR1 (0.73) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| Bisphenol A SCHEMBL1610311 | 0.86 | ESR1 (0.73) | ESR1ESR2CYP3A4ALDH1A1AR | |
| SCHEMBL2290182 | 0.86 | ESR1 (0.58) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| SCHEMBL4450783 | 0.84 | ESR1 (0.73) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| SCHEMBL10865719 | 0.84 | ESR1 (0.73) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| Bisphenol A SCHEMBL811003 | 0.84 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| Bisphenol A SCHEMBL1610315 | 0.84 | SRC (0.61) | ESR1ESR2CYP3A4ALDH1A1LTA4H | |
| SCHEMBL14023390 | 0.84 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456297-A1 | FLAMEPROOF MOLDING MATERIALS | Bayer Aktiengesellschaft (DE) | 2004-09-15 | — | — | EP | disclosed |
| WO-2004041933-A1 | FLAMEPROOF MOLDING MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |
| EP-1404750-A1 | FLAME-PROOFED POLYESTER MOULDING MATERIALS WITH ZNS | BAYER AG (DE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003002643-A1 | FLAME-PROOFED POLYESTER MOULDING MATERIALS WITH ZNS | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-09 | — | — | WO | disclosed |