Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10728839 | 0.98 | NPC1 (0.61) | NPC1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL11037115 | 0.98 | NPC1 (0.60) | NPC1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL11665416 | 0.87 | NPC1 (0.59) | NPC1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL10854322 | 0.86 | NPC1 (0.50) | NPC1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL27475740 | 0.85 | NPC1 (0.65) | NPC1ALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL28853151 | 0.84 | NPC1 (0.56) | NPC1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL501560 | 0.84 | LMNA (0.53) | NPC1ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL27777806 | 0.84 | HTR1A (0.52) | ALDH1A1MAPTABCB1HTTGAA | |
| SCHEMBL9170847 | 0.84 | MAPT (0.48) | NPC1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL27818370 | 0.84 | ADRB1 (0.51) | NPC1MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-1383752-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | Turicum Drug Development AG (CH) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002088100-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | TURICUM DRUG DEVELOPMENT AG (CH) | 2002-11-07 | — | — | WO | disclosed |