Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449457 | 0.76 | MMP12 (0.34) | TSHRMMP12TERTTP53ALDH1A1 | |
| SCHEMBL5573226 | 0.75 | FFAR4 (0.40) | TSHRFFAR4KMT2AALDH1A1 | |
| SCHEMBL9725006 | 0.75 | ALDH1A1 (0.40) | KMT2AALDH1A1 | |
| SCHEMBL6570348 | 0.74 | IMPDH2 (0.39) | TSHRMMP12TP53KMT2APDE3B | |
| SCHEMBL6569085 | 0.73 | MAP3K14 (0.36) | TSHRTERTALDH1A1 | |
| SCHEMBL235690 | 0.72 | MMP12 (0.53) | TSHRMMP12TERTKMT2AALDH1A1 | |
| SCHEMBL30043257 | 0.72 | MMP12 (0.53) | TSHRMMP12TERTKMT2AALDH1A1 | |
| 4,6-Dimethylcoumaranone SCHEMBL7195838 | 0.71 | TSHR (0.46) | TSHRMMP12TERTTP53 | |
| SCHEMBL14883877 | 0.71 | SIRT2 (0.45) | SIRT2PDE3BPDE3A | |
| SCHEMBL4102418 | 0.67 | PDE3B (0.56) | MMP12TP53PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023194892-A1 | DI-SUBSTITUTED BENZODIOXEPINONES COMPOUND AS FRAGRANCES SOURCE AND IN PERFUME COMPOSITIONS | AMBERNATH ORGANICS PVT. LTD. (IN) | 2023-10-12 | — | — | WO | claimed |
| EP-1405851-A1 | Method for producing seven-membered diether compounds and intermediates thereof | Takasago International Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |