SCHEMBL235690

SCHEMBL235690

Cc1ccc2c(c1)OCC(=O)CO2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.53
NPC1 O15118 6/20 0.43
TSHR P16473 2/20 0.43
HTT P42858 2/20 0.43
TERT O14746 1/20 0.42
RAB9A P51151 6/20 0.41
KMT2A Q03164 3/20 0.41
PLK1 P53350 1/20 0.40
CTNNB1 P35222 1/20 0.40
WNT3A P56704 1/20 0.40
CYP19A1 P11511 2/20 0.39
MAPT P10636 5/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 2/20 0.39
HSD17B10 Q99714 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 1/20 0.38
PKM P14618 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30043257 1.00 MMP12 (0.53) MMP12NPC1TSHRHTTTERT
SCHEMBL28477189 0.80 MMP12 (0.50) MMP12NPC1TSHRHTTTERT
SCHEMBL11926931 0.79 MMP12 (0.49) MMP12NPC1TSHRHTTTERT
SCHEMBL11905 0.78 MAPT (0.53) NPC1HTTRAB9AKMT2ACTNNB1
SCHEMBL30452062 0.78 ALDH1A1 (0.55) NPC1HTTRAB9AKMT2AMAPT
SCHEMBL30968 0.78 ALDH1A1 (0.55) NPC1HTTRAB9AKMT2AMAPT
SCHEMBL6570348 0.78 IMPDH2 (0.39) MMP12NPC1TSHRHTTRAB9A
SCHEMBL10962514 0.76 MMP12 (0.46) MMP12TSHRHTTRAB9AKMT2A
SCHEMBL10962220 0.76 MAOB (0.49) MMP12NPC1HTTTERTKMT2A
Hydrochloric Acid SCHEMBL8764874 0.76 ALDH1A1 (0.53) NPC1HTTRAB9AKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1920 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104604-A1 SOLID FRAGRANCE COMPOSITION FIRMENICH SA (CH) 2026-05-21 WO claimed
EP-3541913-B1 FABRIC TREATMENT COMPOSITIONS AND METHODS FOR PROVIDING A BENEFIT PROCTER & GAMBLE (US) 2026-04-22 EP claimed
EP-4711010-A2 PRO-PERFUME COMPOSITIONS Firmenich SA (CH) 2026-03-18 EP claimed
US-12559703-B2 Fragrance composition GIVAUDAN SA (CH) 2026-02-24 US claimed
WO-2025245391-A1 FRAGRANCE COMPOSITIONS WITH CONTROLLABLE ODOR PROFILES TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2025-11-27 WO claimed
US-20250319006-A1 ETHYL 2-CYCLOOCTYLACETATE AS A FRAGRANCE SYMRISE AG (DE) 2025-10-16 US claimed
US-20250302728-A1 FRAGRANCE COMPOSITIONS AND PRODUCTS CONVEYING A POSITIVE MOOD SYMRISE AG (DE) 2025-10-02 US claimed
EP-4615941-A2 SUBSTITUTED 1,3-DIOXOLAN-4-ONES AND 1,3-DIOXAN-4-ONES AS FRAGRANCE INGREDIENTS BASF SE (DE) 2025-09-17 EP claimed
EP-4608360-A1 ANTI-DANDRUFF COMPOSITIONS Firmenich SA (CH) 2025-09-03 EP claimed
EP-4583708-A1 ARTHROPOD CONTROL COMPOSITIONS Firmenich SA (CH) 2025-07-16 EP claimed
US-20090162308-A1 USE OF 2,4'-DIMETHYLPROPIOPHENONE AS A FRAGRANCE SUBSTANCE SYMRISE GMBH & CO. KG (DE) 2009-06-25 US claimed
EP-2072083-A1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma Symrise GmbH & Co. KG (DE) 2009-06-24 EP claimed
EP-2014273-A1 Use of methyl methyl ether and another ether to provide a feeling of cleanliness and purity Symrise GmbH & Co. KG (DE) 2009-01-14 EP claimed
WO-2008050086-A1 FRAGRANCE COMPOSITIONS GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2008-05-02 WO claimed
US-20080096791-A1 a mixture of perfumes selected form esters, aldehydes, alcohols, ketones or plant oils, used for promoting activated, pleasant moods through the inhalation QUEST INTERNATIONAL SERVICES B.V. 2008-04-24 US claimed
US-20080096790-A1 a mixture of perfumes selected form esters, aldehydes, alcohols, ketones or plant oils, used for promoting activated, pleasant moods through the inhalation QUEST INTERNATIONAL SERVICES B.V. 2008-04-24 US claimed
US-20070020210-A1 Methods of reducing the perception of body odors with olfactory adaptation and cross-adapting agents MONELL CHEMICAL SENSES CENTER 2007-01-25 US claimed
US-20060270587-A1 Perfume composition for temperature sense control, sense control article, method of sense control, and perfume map SHISEIDO COMPANY, LTD. (JP) 2006-11-30 US claimed
CN-1845983-A Perfume composition for temperature sense control, sense control article, method of sense control and perfume map SHISEIDO CO LTD (JP) 2006-10-11 CN claimed
EP-1661973-A1 PERFUME COMPOSITION FOR TEMPERATURE SENSE CONTROL, SENSE CONTROL ARTICLE, METHOD OF SENSE CONTROL AND PERFUME MAP Shiseido Co., Ltd. (JP) 2006-05-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319006-A1 ETHYL 2-CYCLOOCTYLACETATE AS A FRAGRANCE ACMSD, FAAH2, FAAH MMP12 3998/4885NPC1 3514/4885TSHR 4779/4885
US-20090162308-A1 USE OF 2,4'-DIMETHYLPROPIOPHENONE AS A FRAGRANCE SUBSTANCE CYP1B1, CYP4A22, ROS1 MMP12 4168/4885NPC1 3810/4885TSHR 4709/4885
US-12559703-B2 Fragrance composition DHCR24, OPRD1, OR10J3 MMP12 4676/4885NPC1 3108/4885TSHR 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.