SCHEMBL6569417

SCHEMBL6569417

CCC(C)P(c1ccccc1)C(C)CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRPA1 O75762 2/20 0.36
TSHR P16473 1/20 0.35
TP53 P04637 1/20 0.35
TAAR1 Q96RJ0 4/20 0.33
SLC6A2 P23975 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
KCNN4 O15554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2550791 0.82 SMN1; SMN2 (0.38) CYP3A4TDP1TP53TAAR1SLC6A2
SCHEMBL16361534 0.81 LMNA (0.38) LMNACYP3A4TDP1TRPA1TSHR
SCHEMBL2305563 0.81 LMNA (0.38) LMNACYP3A4TDP1TRPA1TSHR
SCHEMBL3822018 0.79 POLB (0.39) MEN1KMT2A
SCHEMBL6569748 0.78 LMNA (0.39) LMNACYP3A4TDP1TRPA1TSHR
SCHEMBL20377370 0.77 LMNA (0.35) LMNACYP3A4TDP1TRPA1TSHR
SCHEMBL6285347 0.77 CSNK1E (0.39) SIGMAR1MEN1KMT2A
SCHEMBL3817652 0.76 CSNK1E (0.41) TP53MEN1KMT2A
SCHEMBL8014448 0.74 MAOA (0.37) LMNACYP3A4TDP1TP53TAAR1
SCHEMBL301059 0.74 TDP1 (0.45) LMNACYP3A4TDP1TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927577-B1 Ruthenium metathesis catalyst and method for olefin metathesis using the same TAKASAGO PERFUMERY CO LTD (JP) 2004-06-23 EP disclosed
US-6313365-B1 Ruthenium metathesis catalyst and method for producing olefin reaction product by metathesis reaction using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-11-06 US disclosed
US-6175047-B1 A CATALYST MIXTURE INCLUDING A RUTHENIUM COMPOUND, A DIHALOGENO COMPOUND, A TERMINAL ALKYNE; AS A CATALYST FOR A CARBON-CARBON BOND FORMATION REACTION TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-01-16 US disclosed
EP-0927577-A1 Ruthenium metathesis catalyst and method for producing olefin reaction product by metathesis reaction using the same Takasago International Corporation (JP) 1999-07-07 EP disclosed
US-4529554-A Reacting a sulfonated ligand with unsaturated ketone or aldehyde; then a metal salt GULF RESEARCH & DEVELOPMENT COMPANY (US) 1985-07-16 US disclosed
US-4507247-A PREPARATION OF CATALYSTS FOR THE OLIGOMERIZATION OF ETHYLENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1985-03-26 US disclosed
US-4394322-A INTERMEDIATE FOR CATALYST FOR OLIGOMERIZATION OF ETHYLENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1983-07-19 US disclosed
US-4377528-A CHEMICAL INTERMEDIATES IN THE PREPARATION OF AN OLIGOMERIZATION CATALYST FOR ETHYLENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1983-03-22 US disclosed
US-4377529-A CHEMICAL INTERMEDIATES IN PRODUCTION OF NICKEL YLIDE CATALYSTS FOR OLIGOMERIZATION OF ETHYLENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1983-03-22 US disclosed
EP-0052931-A1 Novel group VA ylides and process for preparing same GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-06-02 EP disclosed
EP-0046329-A1 Process for the oligomerization of ethylene GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
US-4310716-A NICKEL YLIDE CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-01-12 US disclosed
US-4301318-A OBTAINED BY REACTING ETHYLENE USING A NICKEL YLIDE CATALYST; SOLVENT EXTRACTION OF CATALYST USING AMMONIUM HYDROXIDE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-11-17 US disclosed
US-4293727-A CATALYSIS WITH NICKEL YLIDE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-10-06 US disclosed
US-4293502-A CATALYST FOR OLIGOMERIZATION OF ETHYLENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-10-06 US disclosed
US-4080334-A Intermediates in the total synthesis employing substituted isoxazole derivatives HOFFMANN-LA ROCHE INC. (US) 1978-03-21 US disclosed
US-4044004-A Total steroid synthesis employing substituted isoxazole derivatives HOFFMANN-LA ROCHE INC. (US) 1977-08-23 US disclosed
US-3985771-A Total steroid synthesis employing substituted isoxazole derivatives HOFFMANN-LA ROCHE INC. (US) 1976-10-12 US disclosed
US-3984428-A Isoxazolyl-substituted perhydrobenzindenes HOFFMANN-LA ROCHE INC. (US) 1976-10-05 US disclosed
US-3984427-A Preparation of vinyl lactones and corresponding Mannich bases HOFFMANN-LA ROCHE INC. (US) 1976-10-05 US disclosed