Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819570 | 0.87 | GPR84 (0.37) | LMNACYP3A4TDP1TP53GPR84 | |
| SCHEMBL3813023 | 0.83 | ALDH1A1 (0.37) | LMNACYP3A4SMN1; SMN2 | |
| SCHEMBL3816521 | 0.82 | CSNK1E (0.38) | — | |
| SCHEMBL3816365 | 0.81 | AOC3 (0.36) | LMNACYP3A4TDP1TP53GPR84 | |
| SCHEMBL6569406 | 0.80 | LMNA (0.39) | LMNACYP3A4TDP1TP53GPR84 | |
| SCHEMBL6569417 | 0.78 | LMNA (0.38) | LMNACYP3A4TDP1TP53ESR1 | |
| SCHEMBL12761305 | 0.76 | LMNA (0.37) | LMNACYP3A4TDP1TP53GPR84 | |
| SCHEMBL8014448 | 0.76 | MAOA (0.37) | LMNACYP3A4TDP1TP53MAOA | |
| SCHEMBL3823372 | 0.74 | CNR2 (0.36) | SMN1; SMN2 | |
| SCHEMBL28388839 | 0.73 | TAAR1 (0.39) | LMNACYP3A4TDP1TP53GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927577-B1 | Ruthenium metathesis catalyst and method for olefin metathesis using the same | TAKASAGO PERFUMERY CO LTD (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-6313365-B1 | Ruthenium metathesis catalyst and method for producing olefin reaction product by metathesis reaction using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| US-6175047-B1 | A CATALYST MIXTURE INCLUDING A RUTHENIUM COMPOUND, A DIHALOGENO COMPOUND, A TERMINAL ALKYNE; AS A CATALYST FOR A CARBON-CARBON BOND FORMATION REACTION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0927577-A1 | Ruthenium metathesis catalyst and method for producing olefin reaction product by metathesis reaction using the same | Takasago International Corporation (JP) | 1999-07-07 | — | — | EP | disclosed |