Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569630 | 1.00 | HRH3 (0.39) | HRH3STSHSD17B1LMNAMAPT | |
| SCHEMBL4370456 | 0.86 | LMNA (0.42) | HRH3STSHSD17B1LMNAMAPT | |
| SCHEMBL5972920 | 0.79 | LMNA (0.52) | HRH3STSHSD17B1LMNAMAPT | |
| SCHEMBL5972923 | 0.79 | LMNA (0.52) | HRH3STSHSD17B1LMNAMAPT | |
| SCHEMBL13049215 | 0.78 | LMNA (0.40) | STSHSD17B1LMNAMAPTRECQL | |
| SCHEMBL6570677 | 0.75 | HSD17B1 (0.43) | HRH3STSHSD17B1LMNAMAPT | |
| SCHEMBL6570384 | 0.75 | LMNA (0.40) | HRH3STSHSD17B1LMNAMAPT | |
| SCHEMBL6570381 | 0.75 | LMNA (0.40) | HRH3STSHSD17B1LMNAMAPT | |
| SCHEMBL6462339 | 0.75 | ESR1 (0.51) | HRH3STSHSD17B1LMNAMAPT | |
| SCHEMBL6467749 | 0.73 | HRH3 (0.39) | HRH3STSHSD17B1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040059140-A1 | 14(15)-unsaturated 15- and/or 16-substituted androgens with mixed androgen-progrestational profile | VAN DER LOUW JAPP (NL) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059140-A1 | 14(15)-unsaturated 15- and/or 16-substituted androgens with mixed androgen-progrestational profile | HSD17B11, CYP17A1, SHBG | HRH3 3211/4885STS 320/4885HSD17B1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.