Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570152 | 0.85 | SIGMAR1 (0.43) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL491562 | 0.72 | TP53 (0.40) | TP53LMNAADRB2NPSR1SLC6A2 | |
| SCHEMBL6570097 | 0.70 | SIGMAR1 (0.43) | NPSR1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL6570118 | 0.69 | MAPK1 (0.42) | NPSR1ALDH1A1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL22206739 | 0.68 | CHRM2 (0.57) | TP53LMNAADRB2NPSR1SLC6A2 | |
| SCHEMBL22206767 | 0.68 | CHRM2 (0.57) | TP53LMNAADRB2NPSR1SLC6A2 | |
| SCHEMBL16757326 | 0.67 | CYP2D6 (0.66) | LMNANPSR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28751840 | 0.65 | TP53 (0.50) | TP53LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12157071 | 0.65 | ADRB2 (0.48) | TP53LMNAADRB2SLC6A2SLC6A4 | |
| SCHEMBL17084112 | 0.65 | ADRB2 (0.48) | TP53LMNAADRB2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |