Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916195 | 0.87 | HPGD (0.37) | HPGDALDH1A1DEPTORADRA2CMAPT | |
| Bromide SCHEMBL6570241 | 0.86 | HPGD (0.36) | HPGDALDH1A1DEPTORADRA2CMAPT | |
| SCHEMBL150887 | 0.71 | TSHR (0.39) | HPGDALDH1A1DEPTORADRA2CMAPT | |
| SCHEMBL23199903 | 0.68 | NPC1 (0.42) | ALDH1A1SMN1; SMN2TDP1CES1MEN1 | |
| SCHEMBL22245104 | 0.66 | NPC1 (0.40) | ALDH1A1SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL28473056 | 0.66 | DEPTOR (0.37) | HPGDALDH1A1DEPTORMAPTCES1 | |
| SCHEMBL3973751 | 0.64 | NPSR1 (0.36) | ALDH1A1SMN1; SMN2TDP1MEN1CYP3A4 | |
| SCHEMBL10296224 | 0.62 | GSK3B (0.45) | HPGDALDH1A1PTPN1GSK3BADRA2C | |
| SCHEMBL16944257 | 0.62 | ALDH1A1 (0.47) | HPGDALDH1A1PTPN1GSK3BADRA2C | |
| SCHEMBL27463521 | 0.62 | TDP1 (0.50) | HPGDALDH1A1DEPTORMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1407264-A1 | CAGED COMPOUND CLEAVING PROCESS | Cardiogenics Inc. (CA) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003008969-A1 | CAGED COMPOUND CLEAVING PROCESS | CARDIOGENICS INC. (CA) | 2003-01-30 | — | — | WO | disclosed |