Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138894 | 0.90 | VCAM1 (0.46) | VCAM1CYP3A4ALDH1A1TSHRMAPK1 | |
| SCHEMBL3328834 | 0.86 | GPR35 (0.44) | VCAM1CYP3A4ALDH1A1TSHRGPR35 | |
| SCHEMBL8575620 | 0.86 | GPR35 (0.44) | VCAM1CYP3A4ALDH1A1TSHRMAPK1 | |
| SCHEMBL28515553 | 0.85 | PPIA (0.42) | VCAM1ALDH1A1TSHRMAPK1GPR35 | |
| SCHEMBL2977714 | 0.85 | DTYMK (0.50) | VCAM1CYP3A4ALDH1A1TSHRMAPK1 | |
| SCHEMBL29596737 | 0.85 | DTYMK (0.50) | VCAM1CYP3A4ALDH1A1TSHRMAPK1 | |
| SCHEMBL10562304 | 0.85 | VCAM1 (0.49) | VCAM1CYP3A4ALDH1A1TSHRMAPK1 | |
| SCHEMBL3422244 | 0.83 | CYP3A4 (0.57) | VCAM1CYP3A4ALDH1A1TSHRMAPK1 | |
| SCHEMBL8142965 | 0.81 | TSHR (0.43) | CYP3A4ALDH1A1TSHRGPR35MAPT | |
| SCHEMBL2924145 | 0.80 | VCAM1 (0.45) | VCAM1CYP3A4ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | claimed |
| EP-1109550-B1 | NOVEL NITROPHENYLAZIRIDINE COMPOUNDS AND THEIR USE AS PRODRUGS | AUCKLAND UNISERVICES LTD (NZ) | 2004-11-24 | — | — | EP | disclosed |
| US-6517836-B1 | Aziridin-1-yl nitrobenzamides as prodrugs in conjunction with nitroreductase enzymes | AUCKLAND UNISERVICES LIMITED (NZ) | 2003-02-11 | — | — | US | disclosed |
| EP-1109550-A2 | NOVEL NITROPHENYLAZIRIDINE COMPOUNDS AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000013683-A2 | NOVEL NITROPHENYLAZIRIDINE COMPOUNDS AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-03-16 | — | — | WO | disclosed |
| EP-0689092-B1 | Photographic elements containing development accelerators and release compounds that release development inhibitors | EASTMAN KODAK CO (US) | 1998-01-14 | — | — | EP | disclosed |
| EP-0684512-B1 | Photographic elements containing release compounds | EASTMAN KODAK CO (US) | 1997-12-17 | — | — | EP | disclosed |
| EP-0684513-B1 | Photographic elements containing development accelerators and release compounds that release development inhibitors | EASTMAN KODAK CO (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5567577-A | COMPRISING A BLOCKING GROUP FROM WHICH THE PHOTOGRAPHICALLY ACTIVE MOIETY IS RELEASED, A BALLASTING GROUP AND AN AQUEOUS SOLUBILIZING GROUP | EASTMAN KODAK COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0689092-A1 | Photographic elements containing development accelerators and release compounds that release development inhibitors | EASTMAN KODAK COMPANY (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5478711-A | Photographic elements containing development accelerators and release compounds that release development inhibitors | EASTMAN KODAK COMPANY (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0684513-A1 | Photographic elements containing development accelerators and release compounds that release development inhibitors | EASTMAN KODAK COMPANY (US) | 1995-11-29 | — | — | EP | disclosed |
| EP-0684512-A1 | Photographic elements containing release compounds | EASTMAN KODAK COMPANY (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5460932-A | Controlling color balance | EASTMAN KODAK COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0203488-A2 | 7-Azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline carboxylic acids and 1,8-naphthyridine carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |