Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575620 | 0.96 | GPR35 (0.44) | GPR35CASP6CYP3A4MAPTBLM | |
| SCHEMBL6570778 | 0.86 | VCAM1 (0.49) | GPR35CYP3A4MAPTBLMPMP22 | |
| SCHEMBL10627028 | 0.84 | TSHR (0.46) | GPR35CYP3A4MAPTBLMPMP22 | |
| SCHEMBL10483678 | 0.83 | VCAM1 (0.46) | GPR35CASP6CYP3A4ALDH1A1TSHR | |
| SCHEMBL8138894 | 0.83 | VCAM1 (0.46) | GPR35CYP3A4ALDH1A1TSHRVCAM1 | |
| SCHEMBL8142965 | 0.82 | TSHR (0.43) | GPR35CYP3A4MAPTALDH1A1TSHR | |
| SCHEMBL31354849 | 0.82 | ALDH1A1 (0.42) | GPR35CASP6CYP3A4MAPTBLM | |
| SCHEMBL5668778 | 0.82 | ALDH1A1 (0.42) | GPR35CASP6CYP3A4MAPTBLM | |
| SCHEMBL773100 | 0.82 | TSHR (0.47) | GPR35CASP6CYP3A4ALDH1A1TSHR | |
| SCHEMBL11317819 | 0.80 | DTYMK (0.56) | GPR35CASP6CYP3A4MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784554-B | Novel amide group-containing siloxane amine compound | SONY CHEM & INF DEVICE CORP | 2013-07-17 | — | — | CN | disclosed |
| US-8193295-B2 | Amide group-containing siloxane amine compound | SONY CHEMICAL & INFORMATION DEVICE CORPORATION (JP) | 2012-06-05 | — | — | US | disclosed |
| CN-101784554-A | Novel amide group-containing siloxane amine compound | SONY CHEM & INF DEVICE CORP | 2010-07-21 | — | — | CN | disclosed |
| US-20100137547-A1 | NOVEL AMIDE GROUP-CONTAINING SILOXANE AMINE COMPOUND | SONY CHEMICAL & INFORMATON DEVICE CORPORATION (JP) | 2010-06-03 | — | — | US | disclosed |