Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3328834 | 0.96 | GPR35 (0.44) | GPR35ALDH1A1TSHRVCAM1CTSD | |
| SCHEMBL8138894 | 0.87 | VCAM1 (0.46) | GPR35ALDH1A1TSHRVCAM1CYP3A4 | |
| SCHEMBL6570778 | 0.86 | VCAM1 (0.49) | GPR35ALDH1A1TSHRVCAM1CYP3A4 | |
| SCHEMBL5668778 | 0.86 | ALDH1A1 (0.42) | GPR35ALDH1A1TSHRVCAM1CASP6 | |
| SCHEMBL31354849 | 0.86 | ALDH1A1 (0.42) | GPR35ALDH1A1TSHRVCAM1CASP6 | |
| SCHEMBL8142965 | 0.86 | TSHR (0.43) | GPR35ALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL10627028 | 0.84 | TSHR (0.46) | GPR35ALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL10483678 | 0.83 | VCAM1 (0.46) | GPR35ALDH1A1TSHRVCAM1CASP6 | |
| SCHEMBL28515553 | 0.82 | PPIA (0.42) | GPR35ALDH1A1TSHRVCAM1LMNA | |
| SCHEMBL773100 | 0.81 | TSHR (0.47) | GPR35ALDH1A1TSHRVCAM1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770736-A | DIAZONIUM-, AZIDO-, OR AZOCARBOXYLATE-DERIVATIZED POLYPHENYLENE AMIDATE COMPOUNDS | NORTHEASTERN UNIVERSITY (US) | 1998-06-23 | — | — | US | disclosed |