Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152524 | 0.82 | CRHBP (0.41) | L3MBTL1CRHBPCRHR2NPC1RAB9A | |
| SCHEMBL11554855 | 0.72 | MAPT (0.55) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL929085 | 0.69 | MAPT (0.50) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11557189 | 0.69 | MEN1 (0.53) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15228241 | 0.68 | LMNA (0.44) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15953915 | 0.67 | MEN1 (0.52) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5773361 | 0.66 | MEN1 (0.55) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15228242 | 0.65 | LMNA (0.46) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6153096 | 0.65 | TRPV1 (0.39) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6889512 | 0.64 | HTR3A (0.45) | L3MBTL1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406610-A1 | USE OF SUBSTITUTED GAMMA-LACTONE COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2004-04-14 | — | — | EP | claimed |
| WO-2003004016-A1 | USE OF SUBSTITUTED GAMMA-LACTONE COMPOUNDS AS MEDICAMENTS | Grünenthal GmbH (DE) | 2003-01-16 | — | — | WO | claimed |