Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544164 | 0.80 | S1PR2 (0.36) | FFAR1S1PR2BCHEACHE | |
| SCHEMBL5541215 | 0.79 | RECQL (0.49) | FFAR1 | |
| SCHEMBL18919568 | 0.73 | ALDH1A1 (0.41) | FFAR1 | |
| SCHEMBL5547868 | 0.73 | CHRNB2 (0.35) | — | |
| SCHEMBL2096495 | 0.72 | TAAR1 (0.45) | — | |
| SCHEMBL2095678 | 0.70 | TAAR1 (0.52) | — | |
| SCHEMBL6987047 | 0.70 | S1PR2 (0.37) | FFAR1S1PR2 | |
| SCHEMBL1455815 | 0.68 | LOXL2 (0.45) | — | |
| SCHEMBL26582 | 0.67 | CA1 (0.48) | FFAR1 | |
| SCHEMBL5535597 | 0.67 | CYP1A2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469831-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Pfizer Products Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063832-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-08-07 | — | — | WO | disclosed |