Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349172 | 0.85 | SMN1; SMN2 (0.40) | ALDH1A1 | |
| SCHEMBL5898392 | 0.79 | S1PR2 (0.39) | S1PR2FFAR1RECQLLOXLOXL3 | |
| SCHEMBL6987053 | 0.75 | RECQL (0.40) | S1PR2FFAR1RECQLLOXLOXL3 | |
| SCHEMBL5751544 | 0.75 | ALDH1A1 (0.45) | S1PR2FFAR1RECQLALDH1A1RAB9A | |
| SCHEMBL15517369 | 0.75 | FFAR1 (0.33) | S1PR2FFAR1RECQLLOXLOXL3 | |
| SCHEMBL27704309 | 0.75 | TDP1 (0.39) | S1PR2FFAR1RECQLLOXLOXL3 | |
| SCHEMBL9687371 | 0.74 | TSHR (0.44) | — | |
| SCHEMBL190086 | 0.73 | RECQL (0.41) | S1PR2FFAR1RECQLLOXLOXL3 | |
| SCHEMBL23794707 | 0.72 | S1PR2 (0.35) | S1PR2FFAR1RECQL | |
| SCHEMBL5749827 | 0.71 | RAB9A (0.47) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299379-A2 | LACTAM METALLOPROTEASE INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002004416-A2 | LACTAM METALLOPROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |