Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.54 |
| ▸ | RARG | P13631 | 8/20 | 0.54 |
| ▸ | RARA | P10276 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | GOT1 | P17174 | 1/20 | 0.54 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322258 | 0.90 | RARB (0.67) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL6535734 | 0.82 | RARG (0.80) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL851508 | 0.81 | RARA (0.60) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL3322256 | 0.79 | KMT2A (0.48) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL3350688 | 0.78 | RARB (0.54) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL980532 | 0.77 | RARB (0.69) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9334078 | 0.76 | RARB (0.67) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL4747624 | 0.74 | RARB (0.61) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9078617 | 0.73 | RARA (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL1074076 | 0.72 | PKM (0.57) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920312-B1 | APOPTOSIS INDUCING ADAMANTYL DERIVATIVES AND THEIR USAGE AS ANTI-CANCER AGENTS | GALDERMA RES & DEV (FR) | 2004-12-08 | — | — | EP | claimed |