Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.60 |
| ▸ | RARB | P10826 | 5/20 | 0.60 |
| ▸ | RARG | P13631 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.60 |
| ▸ | GOT1 | P17174 | 1/20 | 0.60 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322258 | 0.91 | RARB (0.67) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL3350688 | 0.88 | RARB (0.54) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL3802931 | 0.87 | RARB (0.61) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL3347374 | 0.83 | SLC6A3 (0.44) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL3350681 | 0.82 | SLC6A3 (0.42) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL6571522 | 0.81 | RARB (0.54) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL30698054 | 0.81 | RARB (0.81) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL641921 | 0.81 | RARB (0.81) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL25200687 | 0.80 | RARB (0.69) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL3802353 | 0.80 | RARB (0.53) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139838-B1 | A PROCESS FOR THE PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID | GRINDEKS JSC (LV) | 2012-03-28 | — | — | EP | disclosed |
| EP-1896399-B1 | BIPHENYL AND NAPHTHYL-PHENYL HYDROXAMIC ACID DERIVATIVES | SIGMA TAU IND FARMACEUTI (IT) | 2010-11-17 | — | — | EP | disclosed |
| US-7728039-B2 | Biphenyl and Naphthyl-Phenyl Hydroxamic Acid Derivatives | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2010-06-01 | — | — | US | disclosed |
| US-20100076219-A1 | METHOD FOR PREPARATION OF 6-[3(1-ADAMANTYL) -4-METHOXYPHENYL]-2-NAPHTOIC ACID | JSC GRINDEKS (LV) | 2010-03-25 | — | — | US | disclosed |
| US-20080319082-A1 | Biphenyl and Naphthyl-Phenyl Hydroxamic Acid Derivatives | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-12-25 | — | — | US | disclosed |
| EP-1896399-A1 | BIPHENYL AND NAPHTHYL-PHENYL HYDROXAMIC ACID DERIVATIVES | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007000383-A1 | BIPHENYL AND NAPHTHYL-PHENYL HYDROXAMIC ACID DERIVATIVES | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319082-A1 | Biphenyl and Naphthyl-Phenyl Hydroxamic Acid Derivatives | VHL, ARNT, AHR | RARA 290/4885RARB 136/4885RARG 246/4885 |
| US-20100076219-A1 | METHOD FOR PREPARATION OF 6-[3(1-ADAMANTYL) -4-METHOXYPHENYL]-2-NAPHTOIC ACID | HPD, DERA, DHCR7 | RARA 727/4885RARB 1493/4885RARG 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.