Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571528 | 1.00 | ALDH1A1 (0.44) | ALDH1A1ALOX15USP2POLBEIF4H | |
| SCHEMBL8829009 | 0.72 | ALDH1A1 (0.55) | ALDH1A1ALOX15USP2POLBEIF4H | |
| SCHEMBL14423827 | 0.71 | ALDH1A1 (0.48) | ALDH1A1ALOX15USP2POLBEIF4H | |
| SCHEMBL13681260 | 0.71 | ALDH1A1 (0.48) | ALDH1A1ALOX15USP2POLBEIF4H | |
| SCHEMBL9343844 | 0.71 | MEN1 (0.37) | ALDH1A1ALOX15USP2POLBMEN1 | |
| SCHEMBL987853 | 0.70 | USP2 (0.55) | ALDH1A1ALOX15USP2POLBEIF4H | |
| SCHEMBL987854 | 0.70 | USP2 (0.55) | ALDH1A1ALOX15USP2POLBEIF4H | |
| SCHEMBL8494093 | 0.70 | MAOB (0.44) | ALDH1A1ALOX15USP2POLBEIF4H | |
| SCHEMBL3273188 | 0.68 | ALDH1A1 (0.50) | ALDH1A1ALOX15USP2POLBEIF4H | |
| SCHEMBL8653217 | 0.67 | USP2 (0.37) | ALDH1A1ALOX15USP2POLBEIF4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9901649-B2 | Block copolymers for therapeutic drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-02-27 | — | — | US | disclosed |
| US-20170319704-A1 | BLOCK COPOLYMERS FOR THERAPEUTIC DRUG DELIVERY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-11-09 | — | — | US | disclosed |
| US-9631050-B2 | Antimicrobial cationic polycarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160257782-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-09-08 | — | — | US | disclosed |
| US-8703197-B2 | Branched polyamines for delivery of biologically active materials | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-04-22 | — | — | US | disclosed |
| US-20140080215-A1 | BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-03-20 | — | — | US | disclosed |
| EP-1257542-B1 | METHOD FOR PRODUCING 2-(1,2,4-TRIAZOL-1-YL)-ETHANOLS | BAYER CROPSCIENCE AG (DE) | 2004-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257782-A1 | ANTIMICROBIAL CATIONIC POLYCARBONATES | VDR, GC, CYP24A1 | ALDH1A1 4827/4885ALOX15 1251/4885USP2 3746/4885 |
| US-20170319704-A1 | BLOCK COPOLYMERS FOR THERAPEUTIC DRUG DELIVERY | GSS, GSR, GSTP1 | ALDH1A1 3549/4885ALOX15 797/4885USP2 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.