Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5980986 | 0.82 | GPR3 (0.39) | GPR3EDNRBEDNRAALDH1A1TSHR | |
| SCHEMBL9418161 | 0.81 | RAB9A (0.37) | GPR3HTR7HTR2BTNKS2PBRM1 | |
| SCHEMBL7580105 | 0.77 | ACHE (0.33) | GPR3HTR7HTR2BTNKS2PBRM1 | |
| SCHEMBL30885497 | 0.73 | TNKS2 (0.32) | GPR3HTR2BTNKS2PBRM1NPC1 | |
| SCHEMBL31338566 | 0.71 | GPR3 (0.39) | GPR3HTR7HTR2BTNKS2PBRM1 | |
| SCHEMBL11783880 | 0.71 | HTR2B (0.51) | GPR3HTR7HTR2BTNKS2PBRM1 | |
| SCHEMBL358532 | 0.71 | GPR3 (0.39) | GPR3HTR7HTR2BTNKS2PBRM1 | |
| SCHEMBL28773419 | 0.70 | HTR2B (0.39) | GPR3HTR7HTR2BTNKS2PBRM1 | |
| SCHEMBL1667065 | 0.70 | HTR2A (0.41) | GPR3HTR7HTR2BTNKS2PBRM1 | |
| SCHEMBL17150269 | 0.69 | GPR3 (0.42) | GPR3HTR7HTR2BTNKS2PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637744-A | Bis fluorenyl metallocenes and use thereof | PHILLIPS PETROLEUM COMPANY (US) | 1997-06-10 | — | — | US | claimed |
| EP-0628565-A1 | Bis fluorenyl metallocenes and use thereof | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-14 | — | — | EP | claimed |
| JP-7070161-A | — | — | None | — | — | JP | disclosed |
| EP-1263764-B1 | METHOD OF PREPARING GROUP 14 BRIDGED BISCYCLOPENTADIENYL LIGANDS | EXXONMOBIL CHEM PATENTS INC (US) | 2004-04-14 | — | — | EP | disclosed |
| US-5637744-A | Bis fluorenyl metallocenes and use thereof | PHILLIPS PETROLEUM COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5631335-A | Process of polymerizing olefins using diphenylsilyl or dimethyl tin bridged 1-methyl fluorenyl metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| JP-H0770161-A | BRIDGED SANDWICH LINKAGE METALLOCENE AND PROCESS FOR POLYMERIZING OLEFIN USING SAME AS CATALYST | PHILLIPS PETROLEUM CO | 1995-03-14 | — | — | JP | disclosed |
| EP-0628565-A1 | Bis fluorenyl metallocenes and use thereof | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-14 | — | — | EP | disclosed |