Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583449 | 0.82 | GPR3 (0.41) | ACHEBCHEGPR3HTR2ACHRM2 | |
| SCHEMBL9418161 | 0.81 | RAB9A (0.37) | ACHEGPR3HTR7HTR2BTNKS2 | |
| SCHEMBL6571784 | 0.77 | GPR3 (0.32) | GPR3HTR7HTR2BTNKS2PBRM1 | |
| SCHEMBL3981626 | 0.74 | HTR2A (0.44) | ACHEBCHEGPR3HTR2AHTR7 | |
| SCHEMBL30885497 | 0.73 | TNKS2 (0.32) | GPR3HTR2AHTR2BTNKS2PBRM1 | |
| SCHEMBL7624908 | 0.72 | HTR2A (0.45) | ACHEGPR3HTR2AHTR7HTR2B | |
| SCHEMBL358532 | 0.71 | GPR3 (0.39) | ACHEGPR3HTR2AHTR7HTR2B | |
| SCHEMBL31338566 | 0.71 | GPR3 (0.39) | ACHEGPR3HTR2AHTR7HTR2B | |
| SCHEMBL11783880 | 0.71 | HTR2B (0.51) | ACHEGPR3HTR7HTR2BTNKS2 | |
| SCHEMBL7606771 | 0.70 | HTR2A (0.44) | ACHEBCHEGPR3HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | claimed |
| US-6365764-B1 | METALLOCENE COMPOUNDS HAVING TWO FLUORENYL LIGANDS BRIDGED WITH A SINGLE SILICON OR GERMANIUM ATOM | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-04-02 | — | — | US | claimed |
| EP-0729968-A1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1996-09-04 | — | — | EP | claimed |
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | disclosed |
| US-6180733-B1 | OLEFIN POLYMERIZATION USING CATALYST COMPRISING THE PRODUCT OF REACTION BETWEEN A GROUP 4 OR 5 METALLOCENE COMPOUND AND AN ALUMOXANE, OPTIONALLY WITH ORGANOALUMINUM OR COMPOUND ABLE TO GIVE A METALLOCENE ALKYL CATION; ATACTIC POLYPROPYLENE | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-01-30 | — | — | US | disclosed |
| US-6054404-A | COORDINATION CATALYST | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-04-25 | — | — | US | disclosed |
| EP-0729968-A1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1996-09-04 | — | — | EP | disclosed |