Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571195 | 0.83 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL6570740 | 0.82 | ALDH1A1 (0.38) | CRHR1ALDH1A1PDE10AMEN1PABPC1 | |
| SCHEMBL6570701 | 0.79 | PLA2G7 (0.43) | ALDH1A1PDE10AMEN1PABPC1KMT2A | |
| SCHEMBL855950 | 0.79 | PDE10A (0.44) | ALDH1A1PDE10AMEN1PABPC1KMT2A | |
| SCHEMBL8074928 | 0.79 | ALDH1A1 (0.32) | ALDH1A1PDE10AMEN1PABPC1KMT2A | |
| SCHEMBL7460684 | 0.78 | CYP2A6 (0.37) | ALDH1A1PDE10AMEN1PABPC1KMT2A | |
| SCHEMBL6570840 | 0.78 | ALDH1A1 (0.36) | ALDH1A1PDE10AMEN1PABPC1KMT2A | |
| SCHEMBL6570856 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MEN1PABPC1KMT2ACASP1 | |
| SCHEMBL7459407 | 0.77 | ALDH1A1 (0.35) | ALDH1A1PDE10ACASP1TSHR | |
| SCHEMBL6570914 | 0.77 | MEN1 (0.39) | MEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |