Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530175 | 0.92 | ALDH1A1 (0.42) | PDE10AALDH1A1CASP1TSHRCYP3A4 | |
| SCHEMBL29564357 | 0.91 | ALDH1A1 (0.40) | PDE10AALDH1A1CASP1TSHRCYP3A4 | |
| SCHEMBL6565275 | 0.91 | ALDH1A1 (0.40) | PDE10AALDH1A1CASP1TSHRCYP3A4 | |
| Sulfuric Acid SCHEMBL6566761 | 0.85 | GAA (0.38) | PDE10AALDH1A1CASP1TSHRCYP3A4 | |
| SCHEMBL30848713 | 0.84 | PDE10A (0.42) | PDE10AALDH1A1CASP1TSHRCYP3A4 | |
| SCHEMBL8640578 | 0.81 | CASP1 (0.35) | ALDH1A1CASP1TSHRMAPTMEN1 | |
| SCHEMBL380688 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7775780 | 0.80 | RARA (0.37) | PDE10AALDH1A1CASP1TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL7477515 | 0.80 | ALDH1A1 (0.42) | PDE10AALDH1A1CASP1TSHRCYP3A4 | |
| SCHEMBL3921803 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473025-B1 | Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer | OREAL (FR) | 2012-03-28 | — | — | EP | claimed |
| EP-1493426-B1 | Dyeing composition comprising a developer, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone | OREAL (FR) | 2009-08-12 | — | — | EP | claimed |
| US-7306630-B2 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | L'OREAL S.A. (FR) | 2007-12-11 | — | — | US | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-7141078-B2 | Oxidation dyeing composition for keratinous fiber and dyeing method using same | L′Oreal (FR) | 2006-11-28 | — | — | US | claimed |
| US-7141079-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L′Oreal (FR) | 2006-11-28 | — | — | US | claimed |
| EP-1274393-B1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND METHOD USING SAME | OREAL (FR) | 2006-07-05 | — | — | EP | claimed |
| US-20050000039-A1 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | L'OREAL S.A. (FR) | 2005-01-06 | — | — | US | claimed |
| US-20040194232-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibers | L'OREAL S.A. | 2004-10-07 | — | — | US | claimed |
| US-6783559-B2 | AT LEAST ONE FIRST OXIDATION BASE, AT LEAST ONE SECOND OXIDATION BASE CHOSEN FROM PARA-AMINOPHENOLS, AT LEAST ONE META-AMINOPHENOL AS COUPLER AND AT LEAST ONE ENZYME OF 2-ELECTRON OXIDOREDUCTASE TYPE IN THE PRESENCE OF AT LEAST ONE | L'OREAL S.A. (FR) | 2004-08-31 | — | — | US | claimed |
| US-6342078-B1 | OXIDATION COLOR DYES FOR HAIR WITH METAPHENYLENEDIAMINE COUPLERS | L'OREAL, S. A. (FR) | 2002-01-29 | — | — | US | claimed |
| US-20020007522-A1 | COMPOSITION FOR THE OXIDATION DYEING OF KERATIN FIBRES AND DYEING PROCESS USING THIS COMPOSITION | L' OREAL S.A. | 2002-01-24 | — | — | US | claimed |
| US-20010049850-A1 | Mixture containing 2-amino-3-hydroxypyridine coupler and oxidoreductase enzyme | L'OREAL S.A. (FR) | 2001-12-13 | — | — | US | claimed |
| US-6312479-B1 | OXIDATION BASE; COUPLER CHOSEN FROM 2-AMINO-3-HYDROXYPYRIDINES AND ACID-ADDITION SALTS THEREOF; A 2-ELECTRON OXIDOREDUCTASE; AND A DONOR FOR SAID ENZYME. | L'OREAL S.A. (FR) | 2001-11-06 | — | — | US | claimed |
| EP-0974336-B1 | Composition for oxidative dying of keratinous fibres and dying process therewith | OREAL (FR) | 2001-09-12 | — | — | EP | claimed |
| US-6241784-B1 | COSMETICS OR SKIN COMPOSITION FOR TREATING FIBERS | L'OREAL S.A. (FR) | 2001-06-05 | — | — | US | claimed |
| US-6228129-B1 | OXIDATION BASE, CATIONIC DIRECT DYE AND AN ENZYME OF 2-ELECTRON OXIDOREDUCTASES IN THE PRESENCE OF A DONOR FOR THE ENZYME | L'OREAL S.A. (FR) | 2001-05-08 | — | — | US | claimed |
| US-6152967-A | COMPOSITION FOR HAIR DYEING COMPRISING AT LEAST ONE OXIDATION BASE AND BILIRUBIN OXIDASE | L'OREAL (FR) | 2000-11-28 | — | — | US | claimed |
| US-6099590-A | READY-TO-USE COMPOSITION COMPRISING OXIDATION BASE(S), CHOLINE OXIDASE(S), AND DONOR(S) FOR THE CHOLINE OXIDASE; MULTICOMPARTMENT DYE KITS; PROCESS FOR DYEING; STRONGER COLORATIONS | L'OREAL (FR) | 2000-08-08 | — | — | US | claimed |
| US-6090159-A | READY-TO-USE OXIDATION DYEING COMPOSITION COMPRISING AN OXIDATION BASE, SARCOSINE OXIDASE AS OXIDIZER, AND AT LEAST ONE DONOR FOR THE ENZYME; STRONGER COLORATION, NO BLEACHING | L'OREAL (FR) | 2000-07-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049850-A1 | Mixture containing 2-amino-3-hydroxypyridine coupler and oxidoreductase enzyme | POR, QDPR, DPYD | PDE10A 4233/4885ALDH1A1 202/4885CASP1 3401/4885 |
| US-20050000039-A1 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | FABP4, KRT18, S100A10 | PDE10A 3735/4885ALDH1A1 679/4885CASP1 2571/4885 |
| US-20020007522-A1 | COMPOSITION FOR THE OXIDATION DYEING OF KERATIN FIBRES AND DYEING PROCESS USING THIS COMPOSITION | KRT18, TUBB6, CYBA | PDE10A 3803/4885ALDH1A1 592/4885CASP1 2067/4885 |
| US-20040194232-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibers | KRT18, ALDH1A2, PPOX | PDE10A 1981/4885ALDH1A1 179/4885CASP1 4330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.