Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27692013 | 0.83 | BACE1 (0.40) | TYRBACE1ESR1ESR2GABRA1 | |
| SCHEMBL30597484 | 0.79 | TYR (0.47) | TYRBACE1ESR1ESR2GABRA1 | |
| SCHEMBL4888228 | 0.79 | TYR (0.47) | TYRBACE1ESR1ESR2GABRA1 | |
| SCHEMBL5190973 | 0.79 | TYR (0.41) | TYRBACE1PRKCIACHEALDH1A1 | |
| SCHEMBL652985 | 0.78 | BACE1 (0.40) | BACE1ESR1ESR2GABRA1GABRB2 | |
| SCHEMBL70108 | 0.77 | TYR (0.60) | TYRBACE1ESR1ESR2GABRA1 | |
| SCHEMBL2776271 | 0.77 | ALDH1A1 (0.40) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL11049256 | 0.77 | ATP4A (0.41) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL8977704 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL27952110 | 0.76 | USP2 (0.37) | TYRESR1GABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920853-B1 | Hair dye compositions | P & G CLAIROL INC (US) | 2004-01-21 | — | — | EP | disclosed |
| EP-0920853-A1 | Hair dye compositions | Bristol-Myers Squibb Company (US) | 1999-06-09 | — | — | EP | disclosed |
| US-5696190-A | CURABLE ELASTOMERS MIXED WITH AN ACID SALT OF (DI)ALKYLAMINOALKYL PHENOL | SARTOMER COMPANY (US) | 1997-12-09 | — | — | US | disclosed |