SCHEMBL8977704

SCHEMBL8977704

CCc1ccc(Cc2ccc(CC)c(N)c2C)c(C)c1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
ALDH1A1 P00352 4/20 0.35
HTT P42858 3/20 0.35
MAPT P10636 3/20 0.35
CTRC Q99895 1/20 0.34
POLB P06746 3/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A2 P05177 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP7 P55210 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
DHFR P00374 1/20 0.32
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674174 0.91 GABRA1 (0.36) GABRA1GABRB2ALDH1A1HTTMAPT
SCHEMBL11049256 0.81 ATP4A (0.41) GABRA1GABRB2ALDH1A1HTTMAPT
SCHEMBL2776271 0.81 ALDH1A1 (0.40) ALDH1A1HTTMAPTPOLBGAA
SCHEMBL12797849 0.79 POLB (0.41) GABRA1GABRB2ALDH1A1HTTMAPT
SCHEMBL1259716 0.78 POLB (0.54) ALDH1A1HTTMAPTPOLBGAA
SCHEMBL6572166 0.77 TYR (0.43) GABRA1GABRB2ALDH1A1ALOX15HSD17B10
SCHEMBL11478698 0.77 PRKCI (0.35) ALDH1A1HTTMAPTPOLBTSHR
SCHEMBL3668915 0.77 IKBKB (0.36) ALDH1A1HTTMAPTPOLBGAA
SCHEMBL10341210 0.77 ATP4A (0.43) GABRA1GABRB2ALDH1A1HTTMAPT
SCHEMBL11661917 0.76 POLB (0.52) ALDH1A1HTTMAPTPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0554823-B1 Epoxy resins cured with mixed methylene bridged poly(cyclohexyl-aromatic)amine curing agents AIR PROD & CHEM (US) 1996-04-24 EP disclosed
US-5393806-A Adding a curing accelerator composition containing a mixture of a boron halide and an imidazole ALBEMARLE CORPORATION (US) 1995-02-28 US disclosed
EP-0380029-B1 Bridged bis (cyclohexylamine) curing agents for epoxy resins AIR PROD & CHEM (US) 1994-12-14 EP disclosed
US-5280091-A Polyglycidyl polyether of a polyhydric alcohol AIR PRODUCTS AND CHEMICALS, INC. (US) 1994-01-18 US disclosed
EP-0554823-A1 Epoxy resins cured with mixed methylene bridged poly(cyclohexyl-aromatic)amine curing agents AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-08-11 EP disclosed
US-5098496-A Pulling through die, controlling temperature SHELL OIL COMPANY (US) 1992-03-24 US disclosed
US-4946925-A POLYEPOXIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-08-07 US disclosed
EP-0380029-A2 Bridged bis (cyclohexylamine) curing agents for epoxy resins AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-08-01 EP disclosed
US-4874833-A ELECTRICAL LAMINATE SHELL OIL COMPANY (US) 1989-10-17 US disclosed
US-4775736-A BLEND OF HINDERED AROMATIC DIAMINE AND ACCELERATOR COMPLEX OF BORON TRIFLUORIDE AND A CYCLOAGIPHATIC DIAMINE ETHYL CORPORATION (US) 1988-10-04 US disclosed
EP-0122149-B1 METAL FLUOBORATE CATALYSED HINDERED AROMATIC AMINO CURING AGENTS FOR POLYEPOXIDE RESINS INTEREZ, Inc. (a Georgia corporation) (US) 1988-07-06 EP disclosed
EP-0120666-B1 POLYGLYCIDYL HINDERED AROMATIC AMINES INTEREZ, Inc. (a Georgia corporation) (US) 1987-07-08 EP disclosed
US-4487948-A POLYEPOXIDES, HEAT RESISTANCE, STORAGE STABILITY CELANESE CORPORATION (US) 1984-12-11 US disclosed
EP-0122149-A2 Metal fluoborate catalysed hindered aromatic amino curing agents for polyepoxide resins INTEREZ, Inc. (a Georgia corporation) (US) 1984-10-17 EP disclosed
US-4447586-A Metal fluoborate catalyzed hindered aromatic amine curing agents for polyepoxide resins CELANESE CORPORATION (US) 1984-05-08 US disclosed