Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11536222 | 0.98 | MAPT (0.65) | KDM4EHTTMAPTPOLBALDH1A1 | |
| SCHEMBL5411982 | 0.92 | POLB (0.62) | KDM4EHTTMAPTPOLBALDH1A1 | |
| SCHEMBL4035087 | 0.86 | POLB (0.65) | KDM4EHTTMAPTPOLBALDH1A1 | |
| SCHEMBL1372423 | 0.84 | POLB (0.63) | KDM4EHTTMAPTPOLBALDH1A1 | |
| Water SCHEMBL9248793 | 0.84 | POLB (0.63) | KDM4EHTTMAPTPOLBALDH1A1 | |
| SCHEMBL5121422 | 0.84 | ALDH1A1 (0.61) | KDM4EHTTMAPTPOLBALDH1A1 | |
| SCHEMBL658049 | 0.83 | MAPT (0.59) | KDM4EHTTMAPTPOLBALDH1A1 | |
| SCHEMBL1120589 | 0.83 | GAA (0.59) | KDM4EHTTMAPTPOLBALDH1A1 | |
| SCHEMBL17118308 | 0.83 | POLB (0.58) | KDM4EHTTMAPTPOLBALDH1A1 | |
| SCHEMBL23310021 | 0.83 | POLB (0.66) | KDM4EHTTMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025098683-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF IMEPITOIN | JUSTESA IMAGEN S.A.U. (ES) | 2025-05-15 | — | — | WO | disclosed |
| EP-4553066-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF IMEPITOIN | Justesa Imagen S.A.U. (ES) | 2025-05-14 | — | — | EP | disclosed |
| US-20250049804-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | UNIV INDIANA RES & TECH CORP (US) | 2025-02-13 | — | — | US | disclosed |
| US-12161642-B2 | Ferrochelatase inhibitors and methods of use | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2024-12-10 | — | — | US | disclosed |
| CN-117964504-A | Preparation method of gem-difluoroallylglycine or polypeptide derivative | 南京林业大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117447339-A | Method for preparing alkyl substituted glycine derivative by driving visible light | 沈阳师范大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-113668004-B | Method for electrochemical synthesis of non-natural amino acid derivatives | 浙江工业大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114890908-B | Gamma-trifluoromethyl amino acid derivative and preparation method thereof | 华中科技大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-114890908-A | Gamma-position trifluoromethyl amino acid derivative and preparation method thereof | 华中科技大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-111875544-B | Synthesis method of N-substituted hydantoin compound | 五邑大学 | 2022-04-08 | — | — | CN | disclosed |
| US-4711903-A | ANTIINFLAMMATORY, ANTIALLERGY AGENTS | G. D. SEARLE & CO. (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0235575-A1 | Novel phenolic thioethers as inhibitors of 5-lipoxygenase | G.D. Searle & Co. (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4614739-A | Oxindole derivatives, pharmaceutical compositions and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| US-4542148-A | 2-Oxo-3-phenyl indole derivatives, drugs having a neuroanabolic action containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-17 | — | — | US | disclosed |
| EP-0062887-B1 | INDOLINONE-2 DERIVATIVES, PROCESS FOR THEIR PREPARATION AND NEURO-ANABOLIC MEDIUMS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-11 | — | — | EP | disclosed |
| US-4391816-A | ANTIDIABETIC AGENTS | AYERST, MCKENNA & HARRISON INC. (CA) | 1983-07-05 | — | — | US | disclosed |
| EP-0062887-A1 | Indolinone-2 derivatives, process for their preparation and neuro-anabolic mediums containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-20 | — | — | EP | disclosed |
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4062960-A | Hypolipidemic alkenesulfonamides | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049804-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | FECH, SLC40A1, TPI1 | KDM4E 1246/4885HTT 1798/4885MAPT 3197/4885 |
| US-12161642-B2 | Ferrochelatase inhibitors and methods of use | FECH, SLC40A1, TPI1 | KDM4E 1246/4885HTT 1798/4885MAPT 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.