Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570819 | 0.80 | GRM4 (0.34) | GRM4 | |
| SCHEMBL1177587 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL9666619 | 0.73 | HTR6 (0.32) | — | |
| SCHEMBL13545657 | 0.70 | — | — | |
| SCHEMBL6886042 | 0.69 | — | — | |
| SCHEMBL10571843 | 0.69 | KMT2A (0.33) | — | |
| SCHEMBL9644920 | 0.65 | ALDH1A1 (0.58) | — | |
| SCHEMBL31488031 | 0.64 | GRM4 (0.32) | GRM4 | |
| SCHEMBL1177539 | 0.61 | ALDH1A1 (0.44) | — | |
| SCHEMBL10820872 | 0.61 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133026-B | 1- sulfonyl-pi perdine- 3 -carboxyl i c acid amide derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase for the treatment of type ii diabetes mellitus | HOFFMANN LA ROCHE | 2011-07-06 | — | — | CN | disclosed |
| CN-101133026-A | 1- sulfonyl-pi perdine- 3 -carboxyl i c acid amide derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase for the treatment of type ii diabetes mellitus | HOFFMANN LA ROCHE (CH) | 2008-02-27 | — | — | CN | disclosed |
| EP-1406882-A1 | SUPPORTED CONDENSATION REACTANTS AND METHOD FOR THE PRODUCTION THEREOF | Bayer Chemicals AG (DE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003002546-A1 | SUPPORTED CONDENSATION REACTANTS AND METHOD FOR THE PRODUCTION THEREOF | BAYER CHEMICALS AG (DE) | 2003-01-09 | — | — | WO | disclosed |