Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.32 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571146 | 0.87 | ALDH1A1 (0.40) | RELAS100BF2PRSS1PRSS2 | |
| SCHEMBL6571429 | 0.85 | ALDH1A1 (0.36) | RELAS100BF2PRSS1PRSS2 | |
| SCHEMBL6570799 | 0.84 | GRM2 (0.38) | HDAC2RELAS100BF2PRSS1 | |
| SCHEMBL6572008 | 0.84 | MAPT (0.35) | S100BF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6570859 | 0.84 | S100B (0.37) | S100BF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6570729 | 0.84 | HDAC2 (0.35) | HDAC2S100B | |
| SCHEMBL6571056 | 0.83 | MGAM (0.36) | RELAS100BF2PRSS1PRSS2 | |
| SCHEMBL6571984 | 0.83 | S100B (0.36) | S100BF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6572323 | 0.83 | ALOX15 (0.40) | HDAC2RELA | |
| SCHEMBL6574728 | 0.83 | KMT2A (0.41) | S100BF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| EP-1051143-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |