Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.41 |
| ▸ | RARG | P13631 | 7/20 | 0.41 |
| ▸ | RARA | P10276 | 6/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572077 | 0.90 | PGR (0.39) | ALDH1A1 | |
| SCHEMBL6571107 | 0.87 | KDM4C (0.40) | PTGER4KDM4C | |
| SCHEMBL6572090 | 0.87 | CRHR1 (0.34) | ALDH1A1 | |
| SCHEMBL6572761 | 0.85 | ALDH1A1 (0.42) | RARBRARGRARAMAP4K4ALDH1A1 | |
| SCHEMBL6572455 | 0.84 | USP7 (0.35) | ALDH1A1 | |
| SCHEMBL6572183 | 0.83 | FYN (0.36) | ALDH1A1RXRARXRB | |
| SCHEMBL6571013 | 0.83 | CRHR1 (0.38) | ALDH1A1 | |
| SCHEMBL6571975 | 0.82 | GRM2 (0.38) | MAP4K4ALDH1A1 | |
| SCHEMBL6571986 | 0.82 | MEN1 (0.41) | — | |
| SCHEMBL6572104 | 0.82 | CRHR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |