Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CDC25C | P30307 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574500 | 0.91 | KCNH2 (0.50) | KCNH2SIGMAR1CDC25CBLM | |
| SCHEMBL6574247 | 0.79 | SIGMAR1 (0.42) | KCNH2SIGMAR1MEN1BLMKMT2A | |
| SCHEMBL6574086 | 0.79 | POLB (0.43) | KCNH2MEN1KMT2A | |
| SCHEMBL26239269 | 0.78 | KCNH2 (0.63) | KCNH2SIGMAR1CDC25CMEN1THRB | |
| SCHEMBL7702574 | 0.78 | KCNH2 (0.69) | KCNH2SIGMAR1CDC25CMEN1THRB | |
| SCHEMBL6572322 | 0.77 | MAPT (0.41) | RECQLKMT2ATDP1CHRNB2CHRNA4 | |
| SCHEMBL26239253 | 0.77 | KCNH2 (0.61) | KCNH2SIGMAR1CDC25CMEN1THRB | |
| Hydrochloric Acid SCHEMBL7705362 | 0.77 | KCNH2 (0.67) | KCNH2SIGMAR1CDC25CMEN1THRB | |
| SCHEMBL3929250 | 0.76 | KCNH2 (1.00) | KCNH2SIGMAR1CDC25C | |
| SCHEMBL6572758 | 0.75 | KCNH2 (0.62) | KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |