Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GFER | P55789 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572983 | 0.81 | FNTA (0.42) | MAP4K4KDM4EGAAMAPTGFER | |
| SCHEMBL6571412 | 0.80 | APP (0.47) | KDM4EGAAMAPTGFERCYP3A4 | |
| SCHEMBL3790061 | 0.80 | HTR6 (0.39) | KDM4EMAPTSMN1; SMN2CYP3A4KMT2A | |
| SCHEMBL3788714 | 0.80 | ALDH1A1 (0.48) | NPC1KMT2AHDAC1ALDH1A1HSD17B10 | |
| SCHEMBL6572594 | 0.78 | PTGER4 (0.57) | MAP4K4KDM4EGAAMAPTGFER | |
| SCHEMBL6570748 | 0.78 | TDP1 (0.39) | KDM4EGAAMAPTGFERNPC1 | |
| SCHEMBL1708791 | 0.78 | KMT2A (0.48) | MAP4K4KDM4EGAAMAPTGFER | |
| SCHEMBL25125893 | 0.77 | TP53 (0.52) | MAP4K4KDM4EGFERRXRARXRB | |
| SCHEMBL6573189 | 0.77 | CYP3A4 (0.38) | MAP4K4KDM4ENPC1SMN1; SMN2CYP3A4 | |
| SCHEMBL6575398 | 0.76 | FNTA (0.47) | MAP4K4KDM4EGAAMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |