Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576133 | 0.80 | ABCB1 (0.48) | ABCB1APPCRHBPCRHR2ABCC1 | |
| SCHEMBL1663325 | 0.78 | CRHBP (0.63) | ABCB1CRHBPCRHR2ABCC1KCNMA1 | |
| SCHEMBL28299547 | 0.76 | MAPK1 (0.60) | KCNMA1ALDH1A1TDP1L3MBTL1MAPK1 | |
| SCHEMBL17742439 | 0.75 | TDP1 (0.66) | ABCB1CRHBPCRHR2ABCC1KCNMA1 | |
| SCHEMBL14314156 | 0.75 | ACLY (0.54) | ABCB1APPCRHBPCRHR2ABCC1 | |
| SCHEMBL2332567 | 0.74 | L3MBTL1 (0.65) | APPCRHBPCRHR2ALDH1A1TDP1 | |
| SCHEMBL15940303 | 0.74 | APP (0.48) | ABCB1APPCRHBPCRHR2ABCC1 | |
| SCHEMBL17548845 | 0.74 | CRHBP (0.53) | ABCB1CRHBPCRHR2ABCC1KCNMA1 | |
| SCHEMBL12661135 | 0.74 | CRHBP (0.53) | ABCB1CRHBPCRHR2ABCC1KCNMA1 | |
| SCHEMBL5595131 | 0.74 | CRHBP (0.68) | ABCB1CRHBPCRHR2ABCC1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117899873-A | Transition metal catalyst and preparation method and application thereof | 厦门大学 | 2024-04-19 | — | — | CN | disclosed |
| EP-1091935-B1 | METHOD FOR PREPARING 2-NITRO-5-(PHENYLTHIO)-ANILINES | BAYER CHEMICALS AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| US-6552230-B1 | Amination of a 2,4-dichloronitrobenzene with ammonia forming 5-chloro-2-nitroaniline which is reacted with a thiophenol; one pot process | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| EP-1091935-A2 | METHOD FOR PREPARING 2-NITRO-5-(PHENYLTHIO)-ANILINES | Bayer Aktiengesellschaft (DE) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001669-A2 | METHOD FOR PREPARING 2-NITRO-5-(PHENYLTHIO)-ANILINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-13 | — | — | WO | disclosed |