Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 12/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 12/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 12/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 12/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 12/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | FURIN | P09958 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576397 | 0.86 | MAPT (0.48) | TLR4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6573971 | 0.76 | TLR4 (0.40) | TLR4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6572568 | 0.73 | HTR1A (0.45) | TLR4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6574017 | 0.73 | TLR4 (0.52) | TLR4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6573504 | 0.71 | HTR1A (0.55) | TLR4GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7266211 | 0.70 | TLR4 (0.58) | TLR4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6574739 | 0.67 | GRIN2D (0.59) | TLR4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7030236 | 0.63 | MAPT (0.41) | MAPTALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL6657434 | 0.61 | DDX3X (0.48) | MAPTALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL6576403 | 0.60 | POLB (0.44) | MAPTALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120405-B1 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | OREAL (FR) | 2004-10-27 | — | — | EP | claimed |
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| EP-1120405-A2 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'OREAL (FR) | 2001-08-01 | — | — | EP | claimed |
| EP-1120405-B1 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | OREAL (FR) | 2004-10-27 | — | — | EP | disclosed |
| US-6652600-B2 | Oxidation color dye | L'OREAL S.A. (FR) | 2003-11-25 | — | — | US | disclosed |
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
| EP-1120405-A2 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'OREAL (FR) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | KRT18, OGG1, UNG | TLR4 3637/4885GRIN2D 3837/4885GRIN3B 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.