Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574730 | 0.81 | SLC18A3 (0.50) | SLC18A3SIGMAR1MEN1TP53KMT2A | |
| SCHEMBL15492542 | 0.73 | SLC18A3 (0.51) | SLC18A3SIGMAR1TP53POLB | |
| SCHEMBL27640069 | 0.73 | CA12 (0.49) | SLC18A3SIGMAR1TP53CYP1A2CYP2D6 | |
| SCHEMBL9523945 | 0.73 | ALDH1A1 (0.50) | TSHRCYP2C19ALDH1A1 | |
| SCHEMBL7066218 | 0.72 | SIGMAR1 (0.47) | SLC18A3SIGMAR1TP53ALDH1A1POLB | |
| SCHEMBL3673656 | 0.72 | ALDH1A1 (0.49) | TSHRALDH1A1 | |
| SCHEMBL27510732 | 0.72 | CHRM4 (0.46) | SLC18A3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL7138245 | 0.71 | ALDH1A1 (0.48) | CYP2D6TSHRCYP2C19ALDH1A1 | |
| SCHEMBL8037871 | 0.70 | ALDH1A1 (0.47) | TSHRCYP2C19ALDH1A1 | |
| SCHEMBL7181896 | 0.70 | EPHX1 (0.60) | MEN1TP53TSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409457-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | Sanofi-Aventis (FR) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008381-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | SANOFI-SYNTHELABO (FR) | 2003-01-30 | — | — | WO | disclosed |