Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | OGA | O60502 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15492542 | 0.85 | SLC18A3 (0.51) | SLC18A3SMN1; SMN2HSD11B1KCNH2HRH3 | |
| SCHEMBL27640069 | 0.82 | CA12 (0.49) | SLC18A3SMN1; SMN2HSD11B1KCNH2HRH3 | |
| SCHEMBL10305548 | 0.81 | KCNH2 (0.52) | SLC18A3KCNH2HRH3DRD2PRCP | |
| SCHEMBL6574220 | 0.81 | SLC18A3 (0.51) | SLC18A3ALDH1A1SIGMAR1TP53MEN1 | |
| SCHEMBL31073550 | 0.79 | KCNH2 (0.56) | SLC18A3SMN1; SMN2HSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL7066218 | 0.78 | SIGMAR1 (0.47) | SLC18A3SMN1; SMN2HSD11B1ALDH1A1KCNH2 | |
| SCHEMBL27582497 | 0.77 | KCNH2 (0.45) | SLC18A3SMN1; SMN2HSD11B1KCNH2HRH3 | |
| SCHEMBL420261 | 0.77 | SLC18A3 (0.43) | SLC18A3SMN1; SMN2HSD11B1KCNH2HRH3 | |
| SCHEMBL3192791 | 0.76 | RAB9A (0.51) | SLC18A3SMN1; SMN2HTTALDH1A1KCNH2 | |
| SCHEMBL12918533 | 0.75 | CARM1 (0.57) | SLC18A3SMN1; SMN2ALDH1A1SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409457-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | Sanofi-Aventis (FR) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008381-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | SANOFI-SYNTHELABO (FR) | 2003-01-30 | — | — | WO | disclosed |