Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.46 |
| ▸ | PRCP | P42785 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15492542 | 0.80 | SLC18A3 (0.51) | SIGMAR1SLC18A3PRCPDRD2NPC1 | |
| SCHEMBL27640069 | 0.80 | CA12 (0.49) | SIGMAR1SLC18A3MMP2MMP13NPC1 | |
| SCHEMBL6574730 | 0.78 | SLC18A3 (0.50) | SIGMAR1SLC18A3PRCPDRD2NPC1 | |
| SCHEMBL27582497 | 0.78 | KCNH2 (0.45) | SIGMAR1SLC18A3MMP2MMP13NPC1 | |
| SCHEMBL9042120 | 0.76 | ALDH1A1 (0.57) | SIGMAR1SLC18A3NPC1TP53RAB9A | |
| SCHEMBL10305548 | 0.76 | KCNH2 (0.52) | SLC18A3PRCPDRD2KCNH2HRH3 | |
| SCHEMBL13261229 | 0.73 | SLC18A3 (0.43) | SIGMAR1SLC18A3DRD2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6574220 | 0.72 | SLC18A3 (0.51) | SIGMAR1SLC18A3TP53ALDH1A1POLB | |
| SCHEMBL420261 | 0.71 | SLC18A3 (0.43) | SIGMAR1SLC18A3MMP2MMP13NPC1 | |
| SCHEMBL3192791 | 0.71 | RAB9A (0.51) | SLC18A3NPC1TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058727-A1 | SUBSTITUTED 3,5-DIHYDRO-4H-IMIDAZOL-4-ONES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |