Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574730 | 0.74 | SLC18A3 (0.50) | HTTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6574663 | 0.73 | OGA (0.43) | HTTLMNAKMT2AALDH1A1POLB | |
| SCHEMBL18740794 | 0.69 | ALDH1A1 (0.56) | MAPTHTTMEN1KMT2AGAA | |
| SCHEMBL16197157 | 0.69 | PSEN1 (0.56) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4119679 | 0.68 | SIGMAR1 (0.44) | HTTSMN1; SMN2OGAHRH3 | |
| SCHEMBL28196727 | 0.67 | PSEN1 (0.53) | MEN1KMT2ARAB9ANPC1HRH3 | |
| SCHEMBL31073550 | 0.66 | KCNH2 (0.56) | LMNAMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4002380 | 0.66 | SLC18A3 (0.46) | MAPTHTTLMNAKMT2AGAA | |
| SCHEMBL26986820 | 0.66 | SLC18A3 (0.58) | HTTSMN1; SMN2OGASLC18A3DRD2 | |
| SCHEMBL580852 | 0.66 | PSEN1 (0.49) | MAPTHTTALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409457-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | Sanofi-Aventis (FR) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008381-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | SANOFI-SYNTHELABO (FR) | 2003-01-30 | — | — | WO | disclosed |