Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119679 | 0.93 | SIGMAR1 (0.44) | OGAHTTSMN1; SMN2CHRM4SIGMAR1 | |
| SCHEMBL5671758 | 0.76 | KDM1A (0.49) | SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL5672613 | 0.76 | ACHE (0.54) | POLBALDH1A1LMNAKMT2A | |
| SCHEMBL6574223 | 0.73 | MAPT (0.45) | OGAHTTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL11237070 | 0.73 | SLC18A3 (0.42) | OGASMN1; SMN2ALDH1A1LMNASIGMAR1 | |
| SCHEMBL2768950 | 0.72 | FKBP1A (0.54) | POLBALDH1A1KMT2AGBA1 | |
| SCHEMBL9233648 | 0.72 | KDM4E (0.45) | SMN1; SMN2ALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL6574730 | 0.72 | SLC18A3 (0.50) | OGAHTTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL27393257 | 0.72 | SIGMAR1 (0.52) | SIGMAR1KMT2AGBA1 | |
| SCHEMBL18740793 | 0.70 | ALDH1A1 (0.56) | HTTSMN1; SMN2ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409457-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | Sanofi-Aventis (FR) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008381-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | SANOFI-SYNTHELABO (FR) | 2003-01-30 | — | — | WO | disclosed |