Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.35 |
| ▸ | FEN1 | P39748 | 8/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464302 | 0.87 | BRS3 (0.44) | — | |
| SCHEMBL7458077 | 0.85 | ALDH1A1 (0.34) | POLBALDH1A1 | |
| SCHEMBL9266513 | 0.83 | CA1 (0.38) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL8106979 | 0.81 | ALOX5AP (0.35) | USP30ALOX5APFEN1POLBNSD2 | |
| SCHEMBL7806538 | 0.81 | USP30 (0.34) | USP30ALOX5APFEN1POLBALDH1A1 | |
| SCHEMBL8615855 | 0.81 | NSD2 (0.36) | USP30ALOX5APFEN1NSD2 | |
| SCHEMBL7458447 | 0.77 | GAA (0.50) | ALDH1A1 | |
| SCHEMBL9217889 | 0.77 | USP30 (0.37) | USP30ALOX5APFEN1POLBALDH1A1 | |
| SCHEMBL6574265 | 0.75 | ALOX5AP (0.38) | USP30ALOX5APFEN1CA12CA1 | |
| SCHEMBL7806543 | 0.75 | ALOX5AP (0.36) | USP30ALOX5APFEN1POLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461026-A | Pyridine sulfonyl urea derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-10-24 | — | — | US | disclosed |
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | disclosed |