SCHEMBL8106979

SCHEMBL8106979

CC(=O)OC(c1ncccc1S(=O)(=O)NC(C)(C)C)C(C)F

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 12/20 0.35
FEN1 P39748 12/20 0.35
NSD2 O96028 2/20 0.33
USP30 Q70CQ3 1/20 0.33
POLB P06746 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33
SLC40A1 Q9NP59 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7806538 0.88 USP30 (0.34) ALOX5APFEN1NSD2USP30POLB
SCHEMBL6571896 0.86 ALOX5AP (0.33) ALOX5APFEN1USP30POLB
SCHEMBL8105741 0.83 CA1 (0.38) TRPV4
SCHEMBL9217880 0.81 USP30 (0.35) ALOX5APFEN1NSD2USP30POLB
SCHEMBL8111692 0.81 NSD2 (0.36) ALOX5APFEN1NSD2USP30
SCHEMBL6574265 0.80 ALOX5AP (0.38) ALOX5APFEN1NSD2USP30TRPV4
SCHEMBL8097780 0.77 GAA (0.50)
SCHEMBL9217889 0.77 USP30 (0.37) ALOX5APFEN1NSD2USP30POLB
SCHEMBL7806543 0.72 ALOX5AP (0.36) ALOX5APFEN1NSD2USP30POLB
SCHEMBL8636609 0.72 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788486-B1 HERBICIDAL SULFONYL UREA DERIVATIVES KOREA RES INST CHEM TECH (KR) 2000-07-12 EP disclosed
EP-0788486-A1 HERBICIDAL SULFONYL UREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-08-13 EP disclosed
WO-1996012708-A1 HERBICIDAL SULFONYL UREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-05-02 WO disclosed