Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PON1 | P27169 | 1/20 | 0.38 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572245 | 0.80 | BACE1 (0.54) | BACE1ALOX15ALDH1A1HSD17B10ALOX12 | |
| SCHEMBL5684857 | 0.80 | TSHR (0.54) | BACE1PTGS2PTGS1ALOX15ALDH1A1 | |
| SCHEMBL6029104 | 0.78 | BACE1 (0.62) | BACE1ALOX15ALDH1A1HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL5685645 | 0.78 | TSHR (0.52) | BACE1PTGS2PTGS1ALOX15ALDH1A1 | |
| SCHEMBL13486724 | 0.77 | ACHE (0.48) | BACE1PTGS2PTGS1ALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6781665 | 0.77 | BACE1 (0.60) | BACE1ALOX15ALDH1A1HSD17B10TSHR | |
| SCHEMBL25906335 | 0.74 | TRPA1 (0.48) | BACE1PTGS2PTGS1ALOX15ALDH1A1 | |
| SCHEMBL14283893 | 0.74 | BACE1 (0.55) | BACE1PTGS2PTGS1ALOX15ALDH1A1 | |
| SCHEMBL24254921 | 0.74 | ACHE (0.56) | BACE1PTGS2PTGS1ALDH1A1HSD17B10 | |
| SCHEMBL17251284 | 0.72 | TRPA1 (0.52) | BACE1PTGS2PTGS1ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |