SCHEMBL657474

SCHEMBL657474

C=C(CCCC=CC)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.40
MAOB P27338 6/20 0.40
TOP1 P11387 1/20 0.38
MAPT P10636 2/20 0.36
AKT1 P31749 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PTGS2 P35354 1/20 0.34
EPHX2 P34913 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11409626 0.89 MAOA (0.42) MAOAMAOBMAPTAKT1LMNA
SCHEMBL11409629 0.89 MAOA (0.42) MAOAMAOBMAPTAKT1LMNA
SCHEMBL1140655 0.86 EPHX2 (0.40) MAOAMAOBTOP1MAPTL3MBTL1
SCHEMBL656697 0.81 MAOA (0.42) MAOAMAOBMAPTAKT1L3MBTL1
SCHEMBL9152387 0.80 SOAT2 (0.55) TOP1MAPTLMNATDP1EPHX2
SCHEMBL7986401 0.80 MAOA (0.52) MAOAMAOBMAPTL3MBTL1LMNA
SCHEMBL7984999 0.80 MAOA (0.52) MAOAMAOBMAPTL3MBTL1LMNA
SCHEMBL2380219 0.79 MAOA (0.44) MAOAMAOBMAPTAKT1LMNA
SCHEMBL3031432 0.79 MAOA (0.44) MAOAMAOBMAPTAKT1LMNA
SCHEMBL19590997 0.78 L3MBTL1 (0.62) TOP1MAPTL3MBTL1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150322186-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY PENN STATE RES FOUND (US) 2015-11-12 US claimed
US-9109057-B2 Methods and materials for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2015-08-18 US claimed
WO-2012024614-A2 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION (US) 2012-02-23 WO claimed
US-20120046419-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION 2012-02-23 US claimed
CN-108271378-B Polyolefin interpenetrating network material for hydrocarbon recovery 宾夕法尼亚州立大学研究基金会 2020-07-31 CN disclosed
EP-3350238-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY The Penn State Research Foundation (US) 2018-07-25 EP disclosed
US-9861954-B2 Polyolefin interpenetrated network material for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2018-01-09 US disclosed
US-9688895-B2 Methods and materials for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2017-06-27 US disclosed
US-20170080404-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION 2017-03-23 US disclosed
WO-2017048477-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION (US) 2017-03-23 WO disclosed
US-20160355715-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION 2016-12-08 US disclosed
US-20150322186-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY PENN STATE RES FOUND (US) 2015-11-12 US disclosed
US-9109057-B2 Methods and materials for hydrocarbon recovery THE PENN STATE RESEARCH FOUNDATION (US) 2015-08-18 US disclosed
WO-2012024614-A2 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION (US) 2012-02-23 WO disclosed
US-20120046419-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY THE PENN STATE RESEARCH FOUNDATION 2012-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046419-A1 METHODS AND MATERIALS FOR HYDROCARBON RECOVERY LIPA, HSPH1, HPGDS MAOA 2087/4885MAOB 1502/4885TOP1 360/4885
US-20170080404-A1 POLYOLEFIN INTERPENETRATED NETWORK MATERIAL FOR HYDROCARBON RECOVERY PUF60, PARN, PARG MAOA 4104/4885MAOB 3553/4885TOP1 1139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.