Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30532274 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4183751 | 0.98 | ALDH1A1 (0.46) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL6757387 | 0.88 | ALDH1A1 (0.37) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL14934147 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL718187 | 0.85 | ESR1 (0.40) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL11245521 | 0.81 | AR (0.46) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL29697575 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL657504 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL29505675 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL161784 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EPKMHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4406957-B1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LTD (IE) | 2026-04-08 | — | — | EP | disclosed |
| US-12577256-B2 | Aryl receptor modulators and methods of making and using the same | NOGRA PHARMA LIMITED (IE) | 2026-03-17 | — | — | US | disclosed |
| US-20250129063-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | GENENTECH, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| EP-4522270-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | Genentech Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| US-20250066384-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2025-02-27 | — | — | US | disclosed |
| EP-4406957-A2 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | Nogra Pharma Limited (IE) | 2024-07-31 | — | — | EP | disclosed |
| US-12012418-B2 | Aryl receptor modulators and methods of making and using the same | NOGRA PHARMA LIMITED (IE) | 2024-06-18 | — | — | US | disclosed |
| US-20240132457-A1 | 3-(2-(BENZO[D]THIAZOL-2-YL)-2-(PHENYLSUFONAMIDO)ETHYL)BENZIMIDAMIDE DERIVATIVES AND RELATED COMPOUNDS AS TMPRSS2 INHIBITORS FOR THE TREATMENT OF VIRAL INFECTIONS | INTEGERBIO, INC. | 2024-04-25 | — | — | US | disclosed |
| EP-3160964-B1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | NOGRA PHARMA LTD (IE) | 2024-03-13 | — | — | EP | disclosed |
| WO-2023220237-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | GENENTECH, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-0024016-B1 | TETRACHLOROPHTHALAMIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR BACTERICIDAL USE | BAYER AG (DE) | 1982-02-24 | — | — | EP | disclosed |
| EP-0003099-B1 | N-PHENYL-N'(2-CHLORO-6-FLUORO-BENZOYL) UREA, PREPARATION THEREOF AND USE THEREOF AS INSECTICIDES | BAYER AG (DE) | 1981-09-16 | — | — | EP | disclosed |
| US-4277499-A | Combating insects with N-(substituted-phenyl)-N-(2-chloro-6-fluoro-benzoyl)-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |
| US-4276310-A | ARTHROPODICIDES, FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-30 | — | — | US | disclosed |
| EP-0024016-A1 | Tetrachlorophthalamic acids, process for their preparation and their bactericidal use | BAYER AG (DE) | 1981-02-18 | — | — | EP | disclosed |
| EP-0000156-B1 | 2-ARYLAMINO-3,5-DINITRO-BENZOTRIFLUORIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES. | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |
| EP-0008435-A2 | Substituted N-phenyl-N'-benzoyl-thioureas, their preparation and their use as pesticides | BAYER AG (DE) | 1980-03-05 | — | — | EP | disclosed |
| EP-0003099-A2 | N-phenyl-N'(2-chloro-6-fluoro-benzoyl) urea, preparation thereof and use thereof as insecticides | BAYER AG (DE) | 1979-07-25 | — | — | EP | disclosed |
| EP-0000156-A1 | 2-Arylamino-3,5-dinitro-benzotrifluorides, process for their preparation and their use as pesticides. | BAYER AG (DE) | 1979-01-10 | — | — | EP | disclosed |
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577256-B2 | Aryl receptor modulators and methods of making and using the same | AHR, IL23R, ARNT | ALDH1A1 2164/4885KDM4E 2605/4885PKM 3671/4885 |
| US-20250066384-A1 | ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | AHR, IFNAR1, IL23R | ALDH1A1 948/4885KDM4E 3114/4885PKM 4375/4885 |
| US-12012418-B2 | Aryl receptor modulators and methods of making and using the same | AHR, IL23R, IL2RA | ALDH1A1 774/4885KDM4E 2908/4885PKM 4310/4885 |
| US-20240132457-A1 | 3-(2-(BENZO[D]THIAZOL-2-YL)-2-(PHENYLSUFONAMIDO)ETHYL)BENZIMIDAMIDE DERIVATIVES AND RELATED COMPOUNDS AS TMPRSS2 INHIBITORS FOR THE TREATMENT OF VIRAL INFECTIONS | TMPRSS2, TMPRSS4, TMPRSS11D | ALDH1A1 1094/4885KDM4E 2856/4885PKM 589/4885 |
| US-20250129063-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | VHL, BRCA1, GLS | ALDH1A1 2210/4885KDM4E 1366/4885PKM 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.