SCHEMBL295863

SCHEMBL295863

Nc1cc(C(c2ccc(S)c(N)c2)(C(F)(F)F)C(F)(F)F)ccc1S

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ALDH1A1 P00352 6/20 0.40
KDM4E B2RXH2 3/20 0.40
PKM P14618 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PTPN5 P54829 2/20 0.37
L3MBTL1 Q9Y468 4/20 0.37
MAPT P10636 4/20 0.37
MEN1 O00255 2/20 0.37
GAA P10253 2/20 0.37
KMT2A Q03164 2/20 0.37
GFER P55789 1/20 0.37
CFTR P13569 1/20 0.36
KIF11 P52732 2/20 0.35
LMNA P02545 2/20 0.35
RAB9A P51151 1/20 0.35
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29464084 1.00 ESR1 (0.41) ESR1ESR2ALDH1A1KDM4EPKM
SCHEMBL8510672 0.92 ESR1 (0.36) ESR1ESR2ALDH1A1KDM4EPKM
SCHEMBL657504 0.86 ALDH1A1 (0.52) ALDH1A1KDM4EPKMHPGDHSD17B10
SCHEMBL29697575 0.86 ALDH1A1 (0.52) ALDH1A1KDM4EPKMHPGDHSD17B10
SCHEMBL718187 0.85 ESR1 (0.40) ESR1ESR2ALDH1A1KDM4EPKM
SCHEMBL16593687 0.85 ALDH1A1 (0.39) ESR1ESR2ALDH1A1KDM4EPKM
SCHEMBL6759328 0.84 ALDH1A1 (0.41) ALDH1A1KDM4EPKMHPGDHSD17B10
Hydrochloric Acid SCHEMBL29892011 0.84 ALDH1A1 (0.50) ALDH1A1KDM4EPKMHPGDHSD17B10
Hydrochloric Acid SCHEMBL444567 0.84 ALDH1A1 (0.50) ALDH1A1KDM4EPKMHPGDHSD17B10
Hydrochloric Acid SCHEMBL23411125 0.83 ALDH1A1 (0.48) ALDH1A1KDM4EPKMHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6875554-B2 Positive photosensitive polyimide resin composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-04-05 US claimed
US-12583957-B2 Fluoropolymer-containing composition and molded article DAIKIN INDUSTRIES, LTD. (JP) 2026-03-24 US disclosed
EP-4253432-B1 FLUOROPOLYMER, AQUEOUS LIQUID DISPERSION, COMPOSITION, AND CROSSLINKED PRODUCT DAIKIN IND LTD (JP) 2026-02-25 EP disclosed
US-12509569-B2 Curable fluoropolymer compositions comprising metal fluoride particles and articles therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-12-30 US disclosed
US-20250340727-A1 POLYMER BLEND, CROSSLINKABLE COMPOSITION AND ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-11-06 US disclosed
US-12448466-B2 Method for producing perfluoroelastomer and composition DAIKIN INDUSTRIES, LTD. (JP) 2025-10-21 US disclosed
EP-4632002-A1 POLYMER BLEND, CROSSLINKABLE COMPOSITION, AND ARTICLE Daikin Industries, Ltd. (JP) 2025-10-15 EP disclosed
US-20250171564-A1 METHOD FOR PRODUCING PERFLUOROELASTOMER AND COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2025-05-29 US disclosed
US-20250171614-A1 CROSSLINKABLE ELASTOMER COMPOSITION AND FLUORORUBBER MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-05-29 US disclosed
EP-4556515-A1 METHOD FOR DECOMPOSING FLUORINE-CONTAINING POLYMERS Daikin Industries, Ltd. (JP) 2025-05-21 EP disclosed
EP-1241527-A1 POSITIVE TYPE PHOTOSENSITIVE POLYIMIDE RESIN COMPOSITION Nissan Chemical Industries, Ltd. (JP) 2002-09-18 EP disclosed
EP-1211292-A1 CROSSLINKABLE ELASTOMER COMPOSITION AND MOLDED ARTICLE PRODUCED FROM THE COMPOSITION Daikin Industries, Ltd. (JP) 2002-06-05 EP disclosed
EP-1197517-A1 CROSSLINKABLE ELASTOMER COMPOSITION AND FORMED ARTICLE PREPARED FROM SAID COMPOSITION Daikin Industries, Ltd. (JP) 2002-04-17 EP disclosed
EP-1182230-A1 FILLER FOR CROSSLINKABLE ELASTOMER AND CROSSLINKABLE ELASTOMER COMPOSITION CONTAINING THE SAME Daikin Industries, Ltd. (JP) 2002-02-27 EP disclosed
EP-1153976-A1 FLUOROELASTOMER AND CROSSLINKABLE COMPOSITION THEREOF Daikin Industries, Ltd. (JP) 2001-11-14 EP disclosed
EP-1148081-A1 MOLDED ELASTOMER Daikin Industries, Ltd. (JP) 2001-10-24 EP disclosed
EP-1097948-A1 METHOD OF REDUCING METAL CONTENT IN FLUOROELASTOMER Daikin Industries, Ltd. (JP) 2001-05-09 EP disclosed
EP-0424940-B1 Positive photosensitive polyimide resin composition NISSAN CHEMICAL IND LTD (JP) 1998-01-14 EP disclosed
US-5288588-A Containing diamine substituted with phenolic hydroxyl, carboxyl, thiophenol and/or sulfonic groups NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-02-22 US disclosed
EP-0424940-A2 Positive photosensitive polyimide resin composition NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583957-B2 Fluoropolymer-containing composition and molded article AOC2, AOC1, AOC3 ESR1 1864/4885ESR2 1303/4885ALDH1A1 1097/4885
US-12509569-B2 Curable fluoropolymer compositions comprising metal fluoride particles and articles therefrom TIAM1, CARM1, NPM1 ESR1 2705/4885ESR2 3501/4885ALDH1A1 4194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.