SCHEMBL6575168

SCHEMBL6575168

C=C1[C@H](O)C[C@@H](OCc2ccccc2)C[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.36
OPRM1 P35372 2/20 0.33
OPRL1 P41146 2/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
CTSK P43235 1/20 0.33
SLC18A3 Q16572 1/20 0.33
BCHE P06276 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
PRMT8 Q9NR22 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
FFAR1 O14842 1/20 0.32
BRD4 O60885 1/20 0.31
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4912188 1.00 NAAA (0.36) NAAAOPRM1OPRL1CTSLCTSB
SCHEMBL4912199 1.00 NAAA (0.36) NAAAOPRM1OPRL1CTSLCTSB
SCHEMBL4912191 1.00 NAAA (0.36) NAAAOPRM1OPRL1CTSLCTSB
SCHEMBL4862984 0.92 NAAA (0.37) NAAAOPRM1OPRL1CTSLCTSB
SCHEMBL4861959 0.82 SIGMAR1 (0.39) NAAAOPRM1OPRL1CTSLCTSB
SCHEMBL21028938 0.80 CTSL (0.41) NAAAOPRM1OPRL1CTSLCTSB
SCHEMBL22906947 0.80 CTSL (0.41) NAAAOPRM1OPRL1CTSLCTSB
SCHEMBL21029509 0.80 CTSL (0.41) NAAAOPRM1OPRL1CTSLCTSB
SCHEMBL4862979 0.80 TSHR (0.38)
SCHEMBL14107808 0.79 CTSL (0.37) NAAAOPRM1OPRL1CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210347-B1 CARBOCYCLIC NUCLEOSIDES AND PROCESS FOR OBTAINING SUCH STICHTING REGA V Z W (BE) 2004-06-23 EP disclosed