Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912188 | 0.92 | NAAA (0.36) | NAAACTSLCTSBCTSKOPRM1 | |
| SCHEMBL4912191 | 0.92 | NAAA (0.36) | NAAACTSLCTSBCTSKOPRM1 | |
| SCHEMBL6575168 | 0.92 | NAAA (0.36) | NAAACTSLCTSBCTSKOPRM1 | |
| SCHEMBL4912199 | 0.92 | NAAA (0.36) | NAAACTSLCTSBCTSKOPRM1 | |
| SCHEMBL4861959 | 0.87 | SIGMAR1 (0.39) | NAAACTSLCTSBCTSKOPRM1 | |
| SCHEMBL22906947 | 0.85 | CTSL (0.41) | NAAACTSLCTSBCTSKOPRM1 | |
| SCHEMBL21029509 | 0.85 | CTSL (0.41) | NAAACTSLCTSBCTSKOPRM1 | |
| SCHEMBL21028938 | 0.85 | CTSL (0.41) | NAAACTSLCTSBCTSKOPRM1 | |
| SCHEMBL4862979 | 0.82 | TSHR (0.38) | HTR2BLMNA | |
| SCHEMBL14107854 | 0.82 | OPRM1 (0.33) | NAAACTSLCTSBCTSKOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402688-B2 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin D derivative | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402688-B2 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin D derivative | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1559708-A1 | 2,2-DI-SUBSTITUTED 1a,25-DIHYDROXY-19-NORVITAMIN D DERIVATIVE | Shimizu, Masato (JP) | 2005-08-03 | — | — | EP | disclosed |