SCHEMBL190968

SCHEMBL190968

CC(C)(C)c1cc(Br)cc(C(C)(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.52
GABRB2 P47870 1/20 0.52
POLB P06746 1/20 0.42
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
HIF1A Q16665 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
HTR1D P28221 2/20 0.36
RXRB P28702 4/20 0.35
RXRA P19793 3/20 0.35
RXRG P48443 2/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28241863 0.97 GABRA1 (0.50) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL846677 0.94 GABRA1 (0.46) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL23915436 0.89 GABRA1 (0.44) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL29416703 0.89 GABRA1 (0.44) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL29436334 0.87 RXRB (0.42) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL23909387 0.87 RXRB (0.42) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL1104681 0.87 NOTUM (0.47) GABRA1GABRB2POLBMAPTS1PR1
SCHEMBL13278178 0.87 GABRA1 (0.48) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL31071024 0.86 RXRB (0.41) GABRA1GABRB2POLBKDM4EGAA
SCHEMBL34460149 0.84 POLB (0.41) GABRA1GABRB2POLBMAPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059975-A Eight-membered ring condensed boron dipyrrole compound and preparation method thereof 中国科学院宁波材料技术与工程研究所 2026-05-19 CN claimed
CN-115636736-B Synthesis method of catalyst ligand material 烟台海川化学制品有限公司 2023-05-12 CN claimed
CN-115636736-A Synthesis method of catalyst ligand material 烟台海川化学制品有限公司 2023-01-24 CN claimed
CN-112321639-A Preparation method of aryl diphenylphosphine derivative 河南省科学院化学研究所有限公司 2021-02-05 CN claimed
CN-106946638-B Preparation method of 1, 3-di-tert-butyl-5- (3-methylbutyl-2-yl) benzene 北京六合宁远科技有限公司 2021-01-15 CN claimed
US-20100113800-A1 Formation of Carbon-nitrogen bond SHASUN PHARMA SOLUTIONS LIMITED (GB) 2010-05-06 US claimed
CN-122059975-A Eight-membered ring condensed boron dipyrrole compound and preparation method thereof 中国科学院宁波材料技术与工程研究所 2026-05-19 CN disclosed
CN-118026834-B Preparation method of planar chiral indene metal complex with phenylindene skeleton, synthesis intermediate and catalytic application 中山大学 2026-05-12 CN disclosed
EP-4508056-B1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX DOW GLOBAL TECHNOLOGIES LLC (US) 2026-05-06 EP disclosed
US-20260098005-A1 NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS THE CHEMOURS COMPANY FC, LLC (US) 2026-04-09 US disclosed
EP-4720036-A1 CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF 16380026 Canada Inc. (CA) 2026-04-08 EP disclosed
EP-4720037-A1 CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF 16380026 Canada Inc. (CA) 2026-04-08 EP disclosed
US-12545834-B2 Light-emitting device, display device, electronic device, organic compound, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-02-10 US disclosed
WO-2000076523-A1 METHODS FOR MODULATING FXR RECEPTOR ACTIVITY ALLERGAN SALES, INC. (US) 2000-12-21 WO disclosed
WO-2000077011-A1 ORGANOSILYL COMPOUNDS HAVING NUCLEAR HORMONE RECEPTOR MODULATING ACTIVITY ALLERGAN SALES, INC. (US) 2000-12-21 WO disclosed
US-6160064-A POLYMERIZING MONOMERS IN PRESENCE OF CATALYST SYSTEM COMPRISING UNBRIDGED FLUXIONAL METALLOCENE AND COCATALYST, INTRODUCING ETHYLENE INTO SYSTEM TO INDUCE POLYMERIZATION RATE ENHANCEMENT/ELASTOMERIC PROPERTY ENHANCING EFFECTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-12-12 US disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed
EP-0991675-A1 ETHYLENE ENHANCEMENT OF PROCESSES FOR SYNTHESIS OF HIGH MELTING THERMOPLASTIC ELASTOMERIC $g(a)-OLEFIN POLYMERS (PRE/EPE EFFECTS) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-04-12 EP disclosed
WO-1998057996-A1 ETHYLENE ENHANCEMENT OF PROCESSES FOR SYNTHESIS OF HIGH MELTING THERMOPLASTIC ELASTOMERIC α-OLEFIN POLYMERS (PRE/EPE EFFECTS) THE BOARD OF TRUSTEES OF THE LELAND STANFORD, JR. UNIVERSITY (US) 1998-12-23 WO disclosed
US-4708966-A SUBSTITUTED DI-TERT-BUTYL PHENOL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1987-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098005-A1 NON-FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CBR1, NAF1, CBR3 GABRA1 2347/4885GABRB2 2591/4885POLB 456/4885
US-20100113800-A1 Formation of Carbon-nitrogen bond AOC1, NES, NISCH GABRA1 2065/4885GABRB2 2011/4885POLB 1517/4885
US-12545834-B2 Light-emitting device, display device, electronic device, organic compound, and lighting device TLL1, L1CAM, MAP1LC3A GABRA1 742/4885GABRB2 1177/4885POLB 3955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.