Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 8/20 | 0.55 |
| ▸ | AKR1A1 | P14550 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578359 | 0.86 | AKR1B1 (0.57) | AKR1B1AKR1A1AKR1B10GLO1 | |
| SCHEMBL6575586 | 0.85 | GPR84 (0.58) | AKR1B1AKR1A1MAPTMEN1KMT2A | |
| SCHEMBL6577863 | 0.78 | GPR84 (0.58) | AKR1B1AKR1A1MAPTMEN1KMT2A | |
| Acetic Acid SCHEMBL1598780 | 0.74 | KMT2A (0.49) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL31744797 | 0.72 | MEN1 (0.68) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL21399605 | 0.72 | MEN1 (0.68) | MAPTMEN1KMT2AGPR84AHR | |
| SCHEMBL443331 | 0.71 | AKR1B1 (1.00) | AKR1B1AKR1A1AKR1B10GLO1 | |
| SCHEMBL1098997 | 0.71 | KMT2A (0.50) | AKR1B1AKR1A1MAPTMEN1KMT2A | |
| SCHEMBL31744779 | 0.71 | GPR84 (0.57) | AKR1B1MAPTMEN1KMT2AGPR84 | |
| SCHEMBL3265720 | 0.70 | LOXL2 (0.59) | AKR1B1AKR1A1AKR1B10GLO1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135124-B1 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUDED INDOLEALKANOIC ACIDS | INST FOR PHARM DISCOVERY INC (US) | 2004-04-28 | — | — | EP | disclosed |