Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.53 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577863 | 0.90 | GPR84 (0.58) | GPR84AKR1B1AKR1A1MAPTMEN1 | |
| SCHEMBL6575533 | 0.85 | AKR1B1 (0.55) | GPR84AKR1B1AKR1A1MAPTMEN1 | |
| Acetic Acid SCHEMBL1598780 | 0.77 | KMT2A (0.49) | GPR84MAPTMEN1KMT2AAHR | |
| SCHEMBL6229545 | 0.76 | SMN1; SMN2 (0.56) | AKR1B1AKR1A1MAPTMEN1KMT2A | |
| SCHEMBL28984552 | 0.74 | HDAC6 (0.55) | AKR1B1AKR1A1MAPTMEN1KMT2A | |
| SCHEMBL29007187 | 0.74 | GPR84 (1.00) | GPR84MAPTMEN1KMT2AAHR | |
| SCHEMBL31744779 | 0.73 | GPR84 (0.57) | GPR84AKR1B1MAPTMEN1KMT2A | |
| SCHEMBL6576335 | 0.72 | AKR1A1 (0.53) | GPR84AKR1B1AKR1A1MAPTMEN1 | |
| SCHEMBL28841871 | 0.70 | GPR84 (0.73) | GPR84MAPTMEN1KMT2AAHR | |
| SCHEMBL28841901 | 0.70 | GPR84 (0.73) | GPR84MAPTMEN1KMT2AAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135124-B1 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUDED INDOLEALKANOIC ACIDS | INST FOR PHARM DISCOVERY INC (US) | 2004-04-28 | — | — | EP | disclosed |