Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575563 | 0.94 | ALDH1A1 (0.46) | CTSLMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28209573 | 0.84 | LMNA (0.46) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11326172 | 0.81 | CYP2D6 (0.47) | MAPTLMNA | |
| SCHEMBL16316818 | 0.80 | MEN1 (0.48) | ALDH1A1MEN1KMT2ALMNACA2 | |
| SCHEMBL11205081 | 0.80 | MEN1 (0.48) | ALDH1A1MEN1KMT2ALMNACA2 | |
| SCHEMBL6139152 | 0.80 | MEN1 (0.48) | ALDH1A1MEN1KMT2ALMNACA2 | |
| SCHEMBL10086332 | 0.79 | LMNA (0.50) | ALDH1A1MEN1KMT2ALMNACA2 | |
| SCHEMBL9925979 | 0.79 | LMNA (0.50) | ALDH1A1MEN1KMT2ALMNACA2 | |
| SCHEMBL28052118 | 0.79 | CA2 (0.54) | CTSLMAPTMEN1KMT2ALMNA | |
| SCHEMBL13398403 | 0.79 | MEN1 (0.47) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474405-A2 | PROCESS FOR THE PREPARATION OF 4-HETERO-SUBSTITUTED PHENYLALANINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068725-A2 | PROCESS FOR THE PREPARATION OF 4-HETERO-SUBSTITUTED PHENYLALANINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |