Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254922 | 0.87 | MAOA (0.58) | MAOAMAP4K4CA12CA1CA2 | |
| SCHEMBL3784572 | 0.83 | MCL1 (0.51) | MAOAMCL1MAP4K4CA12CA1 | |
| SCHEMBL3790537 | 0.81 | MAOA (0.52) | MAOAMCL1MAP4K4CA12CA1 | |
| Hydrochloric Acid SCHEMBL5685035 | 0.79 | MAOA (0.50) | MAOAMCL1MAP4K4CA12CA1 | |
| SCHEMBL3786301 | 0.79 | ALDH1A1 (0.58) | MAOAMCL1MAP4K4CA12CA1 | |
| SCHEMBL3790386 | 0.78 | MAP4K4 (0.50) | MAOAMCL1MAP4K4CA12CA1 | |
| SCHEMBL28639432 | 0.78 | MAOA (0.48) | MAOAMCL1MAP4K4CA12CA1 | |
| SCHEMBL3785880 | 0.78 | MAP4K4 (0.50) | MAOAMCL1MAP4K4CA12CA1 | |
| SCHEMBL28447477 | 0.78 | MAP4K4 (0.50) | MAOAMCL1MAP4K4CA12CA1 | |
| SCHEMBL16429067 | 0.77 | KDM1A (0.51) | MAOAMCL1MAP4K4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |